4l18_EF : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX1 AND ETS1 BOUND TO TCR ALPHA PROMOTER (CRYSTAL FORM 3)
reference	Leukemia 28 2040 2014
source	HOMO SAPIENS / MUS MUSCULUS
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;p53-like transcription factors;
reference complex	4l18_B 4l18_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4l18_E interface=29,91,119,120,123,126, vevladhpgelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepRgslsfserlseleql > 4l18_F interface=57,60,63,64, sgpiqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyeKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvkp
interface signature	RRVDRR/KRRY

Estimated binding specificities ?

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# IC=12.603 IC/col=1.050 n_of_columns=12

specificity:

A |  80   0   0  85   0   0   5   0   0   5   6   6
C |   5   0   0   6   0   0   5   0   0  80   5   5
G |   6  96  96   0   0  96   6  96  96   5   5   5
T |   5   0   0   5  96   0  80   0   0   6  80  80

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updated Mon Sep 9 22:53:14 2024