structure nameSTRUCTURE OF HUMAN PARP-1 BOUND TO A DNA DOUBLE STRAND BREAK IN COMPLEX WITH (2Z)-2-{4-[2-(MORPHOLIN-4-YL)ETHOXY]BENZYLIDENE}-3-OXO- 2,3-DIHYDRO-1-BENZOFURAN-7-CARBOXAMIDE
(POLY ADP-RIBOSE POLYMERASE 1)
referenceSteffen et al. J.Med.Chem. 57 5579 2014
sourceHOMO SAPIENS
experimentX-ray (resolution=3.36, R-factor=0.323)
structural superfamilyADP-ribosylation;Domain of polyADP-ribose polymerase;WGR domain-like;
sequence familyPolyADPribose polymerase catalytic domain; PolyADPribose polymerase, regulatory doma; WGR domain;
multimeric complexes4dqy_AD 4dqy_BF 4dqy_CE 4opx_AD 4oqa_AD 4oqb_AD
reference complex4dqy_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB

No structural evidence for specific binding to DNA (<4 informative columns)


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updated Thu Sep 12 19:56:25 2024