interface graph thumbnail
legend  pdf

structure name1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS AND SOLUTION STRUCTURE FOR PARP-1 F1F2 DOMAINS IN COMPLEX WITH A DNA SINGLE-STRAND BREAK
(POLY ADP-RIBOSE POLYMERASE 1)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyPolyADPribose polymerase and DNALigase Z;
multimeric complexes4av1_ABCD
redundant complexes4av1_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSFVPRQLI

Estimated binding specificities ?

contactlogo
# IC=10.807 IC/col=0.240 n_of_columns=45 specificity:   
A |   0  24  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  33  24   0   0   0  24  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  10   0  24   0
C |   0  24  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  21  24  96   0  96  24  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  44   0  24   0
G |  96  24  24  96  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  21  24   0   0   0  24  24  96  24  24  24  24  24  24  24  24  24  24  24  24  24  24  21  96  24  96
T |   0  24  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  21  24   0  96   0  24  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  21   0  24   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --RGSTFGVTPCRG--QCLCIG   L               +------------2n8a_A    
                                  +--------1 
  ------------RGKG--LCIG       +--2        +------------3odc_B    
                               !  ! 
  --RG--FCVGPG----------     --3  +---------------------3od8_G    
                               ! 
  STRG------------------       +------------------------4av1_A

home
updated Fri Sep 13 16:30:21 2024