4r2c_A : 3D-footprint complex

structure name	EGR1/ZIF268 ZINC FINGERS IN COMPLEX WITH HYDROXYMETHYLATED DNA (Early growth response protein 1)
reference	Olanrewaju et al. 'Genes 28 2304 2014
source	Homo sapiens
experiment	X-ray (resolution=1.89, R-factor=0.201)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
multimeric complexes	1p47_AB
reference complex	4x9j_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4r2c_A interface=17,19,20,23,45,47,48,51,73,75,76,79, erpyacpvescdrrfsRsDEltRhirihtgqkpfqcricmrnfsRsDHltThirthtgekpfacdicgrkfaRsDErkRhtkihlr
interface signature	RDERRDHTRDER

Estimated binding specificities ?

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# IC=10.183 IC/col=1.131 n_of_columns=9

specificity:

A |  38   0   0   0   0  96   0   0   1
C |  20   0  96  96  96   0  96   0  76
G |  19  96   0   0   0   0   0  96   0
T |  19   0   0   0   0   0   0   0  19

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updated Fri Jan 9 01:32:49 2026