4z2d_ABCD : 3D-footprint complex

structure name	QUINOLONE(LEVOFLOXACIN)-DNA CLEAVAGE COMPLEX OF GYRASE FROM S. PNEUMONIAE
reference	Crevel et al. 'To ? ? ?
source	STREPTOCOCCUS PNEUMONIAE
experiment	X-ray (resolution=3.38, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	4z2c_D 6n1p_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4z2d_A interface=21,29,171, qdknlvnvnltkemkasfidYamsvivaRalpdvrdglkpvhrrilygmnelgvtpdkphkksaritgdvmgkyhphgdssiyeamvrmaqwwsyrymlvdghgnfgsmdgdsaaaqrytearmskialemlrdinkntvdfvdnydanereplvlparfpnllvngatgIavgmatnipphnlgetidavklvmdnpevttkdlmevlpgpdfptgalvmgksgihkayetgkgsivlrsrteiettktgrerivvtefpymvnktkvhehivrlvqekriegitavrdesnregvrfvievkrdasanvilnnlfkmtqmqtnfgfnmlaiqngipkilslrqildayiehqkevvvrrtrfdkekaearahilegllialdhideviriirasetdaeaqaelmskfklserqsqaildmrlrrltglerdkiqseyddllaliadladilakpervsqiikdeldevkrkfsdkrrtelmv > 4z2d_B interface=171, qdknlvnvnltkemkasfidyamsvivaralpdvrdglkpvhrrilygmnelgvtpdkphkksaritgdvmgkyhphgdssiyeamvrmaqwwsyrymlvdghgnfgsmdgdsaaaqrytearmskialemlrdinkntvdfvdnydanereplvlparfpnllvngatgIavgmatnipphnlgetidavklvmdnpevttkdlmevlpgpdfptgalvmgksgihkayetgkgsivlrsrteivvtefpymvnktkvhehivrlvqekriegitavrdesnregvfvirdasanvilnnlfkmtqmqtnfgfnmlaiqngipkilslrqildayiehqkevvvrrtrfdkekaearahilegllialdhideviriirasetdaeaqaelmskfklserqsqaildmrlrrltglerdkiqseyddllaliadladilakpervsqiikdeldevkrkfsdkrrtelmv > 4z2d_C interface=58, khmksgleisnlpgkladcssnnpaetelfivegdsaggsaksgrnrefqailpirgKilnvekasmdkilaneeirslftamgtgfgaefdvskaryqklvlmtdadvdgahirtllltliyrymkpileagyvyiaqpplgemddhqlwettmdpehrlmarvsvddaaeadkifdmlmgdrveprrefieenavy > 4z2d_D interface=53, mksgleipgkladcssnnpaetelfivegdsaggsaksgrnrefqailpirgKilnvekasmdkilaneeirslftamgtgfgaefdvskaryqklvlmtdadvdgahirtllltliyrymkpileagyvyiaqpplgemddhqlwettmdpehrlmarvsvddaaeadkifdmlmgdrveprrefieenavys
interface signature	YRI/I/K/K

Estimated binding specificities ?

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# IC=6.782 IC/col=0.484 n_of_columns=14

specificity:

A |   0   0  21  96  21  24  24  24  24  24  24  24   0  96
C |   0   0  21   0  21  24  24  24  24  24  24  24  96   0
G |   0  96  12   0  21  24  24  24  24  24  24  24   0   0
T |  96   0  42   0  33  24  24  24  24  24  24  24   0   0

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updated Fri Dec 15 22:20:58 2023