interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2A:ARNT COMPLEX WITH HRE DNA
referenceRastinejad et al. Nature 524 303 2015
sourceMUS MUSCULUS
experimentX-ray (resolution=3.60, R-factor=?)
structural superfamilyPYP-like sensor domain PAS domain;HLH, helix-loop-helix DNA-binding domain;
reference complex4zpk_A 4zpk_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHERR/SARR

Estimated binding specificities ?

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# IC=6.383 IC/col=0.912 n_of_columns=7 specificity:   
A |  75   0   0   0   9   7   7
C |   7  96   0   0   7  75   7
G |   7   0  96   0  73   7  75
T |   7   0   0  96   7   7   7
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updated Tue Sep 10 01:23:22 2024