interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-1A:ARNT COMPLEX WITH HRE DNA
referenceRastinejad et al. Nature 524 303 2015
sourceMUS MUSCULUS
experimentX-ray (resolution=3.90, R-factor=?)
structural superfamilyPYP-like sensor domain PAS domain;HLH, helix-loop-helix DNA-binding domain;
reference complex4zpk_A 4zpr_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHERR/RSRARR

Estimated binding specificities ?

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# IC=5.807 IC/col=0.968 n_of_columns=6 specificity:   
A |  13   0  96   0   0  13
C |  16  96   0  96   0  13
G |  54   0   0   0  96  13
T |  13   0   0   0   0  57
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updated Tue Sep 10 01:23:38 2024