interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF TRMBL2, AN ARCHAEAL CHROMATIN PROTEIN, SHOWS A NOVEL MODE OF DNA BINDING.
(Putative HTH-type transcriptional regulator TrmBL2)
referenceDiederichs et al. J.Mol.Biol. 427 3216 2015
sourcePyrococcus furiosus
experimentX-ray (resolution=2.50, R-factor=0.227)
structural superfamily"Winged helix" DNA-binding domain;Phospholipase D/nuclease;
sequence familySugarspecific transcriptional regulator Trm;
multimeric complexes5box_ABCD 5bpd_ABCD 5bpi_ABCD
reference complex5bpd_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYPPRY

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4 specificity:   
A |  16  96   0  54
C |  13   0   0  13
G |  54   0   0  16
T |  13   0  96  13
scan!

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updated Fri Jan 9 02:42:20 2026