5ego_AB : 3D-footprint complex

structure name	HOXB13-MEIS1 HETERODIMER BOUND TO METHYLATED DNA
reference	Morgunova et al. Science 356 ? 2017
source	HOMO SAPIENS
experiment	X-ray (resolution=2.54, R-factor=?)
structural superfamily	Homeodomain-like;
reference complex	4xrm_B 5ego_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5ego_A interface=44,47,48,51,52, afpkvatnimrawlfqhlthpypseeqkkqlaqdtgltilqvnNwfINarRRivqpm > 5ego_B interface=1,4,46,49,50, RkkRipyskgqlrelereyaankfitkdkrrkisaatslserqitIwfQNrrvkekkvlakvk
interface signature	NINRR/RRIQN

Estimated binding specificities ?

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# IC=12.429 IC/col=0.888 n_of_columns=14

specificity:

A |  13  24  24   0  96  96  96  24  16   0   0   0   0  96
C |  13  24  24   0   0   0   0  24  54   0   0   0  96   0
G |  16  24  24   0   0   0   0  24  13   0  96   0   0   0
T |  54  24  24  96   0   0   0  24  13  96   0  96   0   0

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updated Mon Jan 5 16:10:51 2026