7psx_B : 3D-footprint complex

structure name	STRUCTURE OF HOXB13 BOUND TO HYDROXYMETHYLATED DNA (Homeobox protein Hox-B13)
reference	Morgunova et al. 'To ? ? ?
source	Homo sapiens
experiment	X-ray (resolution=2.00, R-factor=0.261)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	5edn_AJ 5edn_BG 5eg0_AB 5ego_AB 5no6_AN 5no6_BI
redundant complexes	5edn_G 5eea_G 5ef6_G 5ego_B 5eg0 5no6
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7psx_B interface=3,45,48,49,56, kkRipyskgqlrelereyaankfitkdkrrkisaatslserqitIwfQNrrvkekKvlak
interface signature	RIQNK

Estimated binding specificities ?

readout + contact

# IC=7.278 IC/col=0.485 n_of_columns=15

specificity:

A |   4  24  24  24  24  24  24   4   4  96   0  16  96  24   5
C |   4  24  24  24  24  24  24   4   0   0   0  18   0  24   4
G |  25  24  24  24  24  24  24   5   5   0   0  50   0  24  83
T |  63  24  24  24  24  24  24  83  87   0  96  12   0  24   4

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RA----------IAQTNAMC--   L           +-----------------------------1puf_A    
                                     +-3 
  ------------ITKGNARGRA   L         ! +-----------------------------1zq3_P    
                                   +-4 
  RT----------NT--NAIARG   L       ! !                             +1b72_B    
                                   ! !              +--------------1 
  ------YTVCKGDCKC------   L     +-5 +--------------2              +2qhb_A    
                                 ! !                ! 
  --HTRA------NCATATAT--   L     ! !                +--------------1le8_B    
                               +-6 ! 
  RA----------ITQTNAMG--   L   ! ! +-----------------------------5zjt_E    
                             --7 ! 
  RA----------ITQCNAMC--   L   ! +-----------------------------1b8i_A    
                               ! 
  --RT--------NT--NAIARG   L   +-----------------------------4cyc_B

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updated Tue Dec 19 20:21:00 2023