7psx_B : 3D-footprint complex

structure name	STRUCTURE OF HOXB13 BOUND TO HYDROXYMETHYLATED DNA (Homeobox protein Hox-B13)
reference	Morgunova et al. 'To ? ? ?
source	Homo sapiens
experiment	X-ray (resolution=2.00, R-factor=0.261)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	5eg0_AB 5ego_AB 5no6_AN 5no6_BI 8byx_AK 8byx_BJ 8byx_GL
redundant complexes	5ego_B 8byx_B 5eg0 5no6
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7psx_B interface=3,45,48,49,56, kkRipyskgqlrelereyaankfitkdkrrkisaatslserqitIwfQNrrvkekKvlak
interface signature	RIQNK

Estimated binding specificities ?

readout + contact

# IC=7.669 IC/col=0.511 n_of_columns=15

specificity:

A |   0  24  24  24  24  24  24   0   6  96   0  15  96  24   0
C |   5  24  24  24  24  24  24   0   5   0   0  21   0  24  25
G |  26  24  24  24  24  24  24   0   0   0   0  35   0  24  71
T |  65  24  24  24  24  24  24  96  85   0  96  25   0  24   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RTQTVAQTNA----------   L                              +8osb_E    
                                         +--------------1 
  RT--VTKGNA------KA--   L             +-3              +2lkx_A    
                                       ! ! 
  ----NCICNARGRG------   L     +-------4 +--------------4xrm_B    
                               !       ! 
  RT--IAQCNA----MG----   L     !       !            +---1b72_A    
                             +-5       +------------2 
  RC--IAQCNA----YC----   L   ! !                    +---3rkq_B    
                           --6 ! 
  ----VTCCNA----QA--RT   L   ! +------------------------8g87_X    
                             ! 
  --------------YCFAKC       +-------------------------6pe2_B

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updated Sat Sep 14 04:20:46 2024