interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF A TRANSCRIPTION FACTOR AND DNA COMPLEX
(Transcription factor MYC2)
referenceLian et al. 'Cell 19 1334 2017
sourceArabidopsis thaliana
experimentX-ray (resolution=2.70, R-factor=0.209)
structural superfamilyHLH, helix-loop-helix DNA-binding domain;
sequence familyHelixloophelix DNAbinding domain;
multimeric complexes5gnj_AB 5gnj_GIN
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHERR

Estimated binding specificities ?

contactlogo
# IC=4.046 IC/col=0.809 n_of_columns=5 specificity:   
A |  67   0  96   9   9
C |   9  96   0  69   9
G |   9   0   0   9  69
T |  11   0   0   9   9
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: MYC2
CACATGPubMed5gnj_I(2.62e-03), 5gnj_AB(1.16e-04), 5gnj_GIN(7.77e-05)
CANNTGPubMed5gnj_AB(6.34e-03), 5gnj_GIN(3.42e-03)
ATACGTGTPubMed5gnj_I(1.62e-06), 5gnj_AB(1.22e-06), 5gnj_GIN(1.87e-04)
AACGTGPubMed5gnj_I(3.55e-04), 5gnj_AB(1.83e-05), 5gnj_GIN(7.27e-06)

Dendrogram of similar interfaces ?

matrix format
  
  HG----ETRCRG   L                    +5gnj_I    
                                    +-1 
  HGNT--ECRCRG   L                +-2 +1nkp_E    
                                  ! ! 
  HGNT--ECRCRG   L        +-------3 +1nkp_A    
                          !       ! 
  HGNTMTEARCRG   L   +----4       +-1nlw_D    
                     !    ! 
  --RG--------   L --5    +---------6od3_F    
                     ! 
  HGNTLGECRCRC   L   +--------------5i50_B    
                   

home
updated Fri Sep 13 19:38:07 2024