5gq9_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS ARGONAUTE IN COMPLEX WITH G1C SIDNA AND DNA TARGET (Thermus thermophilus Argonaute)
reference	Sheng et al. 'To ? ? ?
source	Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) / Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
experiment	X-ray (resolution=2.70, R-factor=0.192)
structural superfamily	Ribonuclease H-like;
sequence family	Piwi domain 502;
multimeric complexes	3hk2_AB 3hvr_AB
reference complex	4n41_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5gq9_B interface=41,42,57,260,433,434,437,536,598,599,603,635, hlgktevflnrfalrplnpeelrpwrlevvldpppgreevYPllaqvarraggvtvRmgdglaswsppevlvlegtltyayrlypkgrrpldpkdpgersvlsalarrllqerlrrlegvwveglavyrrehargpgwrvlggavldlwvsdsgafllevdpayrilcemsleawlaqghplpkrvrnaydrrtwellrlgeedpkelplpgglslldyhaskgrlqgreggrvawvadpkdprkpiphltgllvpvltLedlslalslpweerrrrtreiaswigrrlglgtpeavraqayrlsipklmgrravskpadalrvgfyraqetalallrldgaqgwpeflrrallrafgasgaslrlhtlhahpsqglafrealrkakeegvqavlvltppmawedrnrlkalllreglpsqilnvplreeerHRweNallgllakaglqvvalsgaypaelavgfdaggresfrfggaacavggdgghllwtlpeaqageripqevvwdlleetlwafrrkagrlpsrvlllrdgRvpqdefalalealaregiaydlvsvrksgggrvypvqgrladglyvpledktfllltvhrdFRgtpRplklvheagdtplealahqifhltrlypasgFafprlpaplhladrlvkevgrlgirhlkevdreklffv
interface signature	YPRLHRNRFRRF

Estimated binding specificities ?

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# IC=4.434 IC/col=0.296 n_of_columns=15

specificity:

A |   0  24  13   0  24  54  24  24  24  24  24  24  24  24   0
C |   0  24  16   0  24  16  24  24  24  24  24  24  24  24   0
G |  96  24  54  96  24  13  24  24  24  24  24  24  24  24   0
T |   0  24  13   0  24  13  24  24  24  24  24  24  24  24  96

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updated Thu Sep 12 21:20:11 2024