5i2d_R : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF T. THERMOPHILUS TTHB099 CLASS II TRANSCRIPTION ACTIVATION COMPLEX: TAP-RPO
reference	Ebright et al. Science 352 1330 2016
experiment	X-ray (resolution=4.41, R-factor=0.242)
structural superfamily	cAMP-binding domain-like;"Winged helix" DNA-binding domain;
sequence family	Cyclic nucleotidebinding domain; Bacterial regulatory proteins, crp famil;
multimeric complexes	5i2d_CDFGH 5i2d_NOQRS
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5i2d_R interface=152,153,154,155,157,158, mkrfarketiylrgeeartlyrleeglvrvvellpdgrlitlrhvlpgdyfgeealegkayrytaeamteavvqglepramdhealhrvarnlarqmrrvqayeahlqtgelrariaryllfladtplsardrqgiyvtvsheeiadatasIRESvSKvladlrregliatayrrvylldlaalereagsaleaa
interface signature	IRESSK

Estimated binding specificities ?

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# IC=4.250 IC/col=0.850 n_of_columns=5

specificity:

A |   0  12   0   0  60
C |   0  12   0   0  12
G |   0  60  12  96  12
T |  96  12  84   0  12

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----ITRGECSCSGKG----------   L                               +5i2d_R    
                                       +-----------------------1 
  ----HT--STATSTRG----------   L     +-3                       +5lej_A    
                                     ! ! 
  ETNTSCRGHC--RT--------QA--   L   +-4 +------------------------5d4s_B    
                                   ! ! 
  --------------RCYG--KT----     --5 +--------------------------2acj_B    
                                   ! 
  ----TT--PTTCSTNT--------RT   L   !                          +4lln_I    
                                   +--------------------------2 
  --NGLTKTPTSTTT----RT------   L                              +7el3_B

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updated Fri Sep 13 19:49:26 2024