structure nameHUMAN HOLO-PIC IN THE OPEN STATE
sourceHOMO SAPIENS
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;P-loop containing nucleoside triphosphate hydrolases;
reference complex5iy6_M 5iy6_N 5iy6_P 5iy6_T 5iy6_V
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKKR/YKDH//SNDKATRDSQKNSKNRTMRM/PLNSEDEQELHDGILNRDKG/NVFLFVTNVFPLFVT/KH/L

Estimated binding specificities ?

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# IC=25.050 IC/col=0.716 n_of_columns=35 specificity:   
A |   6  24  24   0  24   3  24   9   0  96   0   9  96  96   3   0  24   0   0   8  24  24  24  24  24  24  24  24   0   0   3   0   0  96   0
C |  84  24  24  96  24   3  24   7   0   0  96   7   0   0  84   0  24   0  96  70  24  24  24  24  24  24  24  24  96   0   6   0   0   0   0
G |   3  24  24   0  24  84  24  73  96   0   0  73   0   0   3  96  24  96   0  11  24  24  24  24  24  24  24  24   0   0   3   0   0   0   0
T |   3  24  24   0  24   6  24   7   0   0   0   7   0   0   6   0  24   0   0   7  24  24  24  24  24  24  24  24   0  96  84  96  96   0  96
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updated Mon Jan 5 17:53:40 2026