structure nameHUMAN HOLO-PIC IN THE OPEN STATE
sourceHOMO SAPIENS
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;P-loop containing nucleoside triphosphate hydrolases;
reference complex5iy6_M 5iy6_N 5iy6_P 5iy6_T 5iy6_V
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKKR/YKDH//SNDKATRDSQKNSKNRTMRM/PLNSEDEQELHDGILNRDKG/NVFLFVTNVFPLFVT/KH/L

Estimated binding specificities ?

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# IC=26.254 IC/col=0.750 n_of_columns=35 specificity:   
A |  96   0  96  96  93  96   0  24  24  24  24  24  24  24  24  10   0   0  10   0   5  96  96  10   0   0   0   9  24   0  24   0  24  24   3
C |   0   0   0   0   0   0   0  24  24  24  24  24  24  24  24  10   0  96  10  96   3   0   0  10   0   0   0   6  24   0  24   0  24  24   3
G |   0   0   0   0   0   0  96  24  24  24  24  24  24  24  24  66  96   0  66   0  85   0   0   8   0   0   0   6  24   0  24   0  24  24  87
T |   0  96   0   0   3   0   0  24  24  24  24  24  24  24  24  10   0   0  10   0   3   0   0  68  96  96  96  75  24  96  24  96  24  24   3
scan!

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updated Wed Jul 30 08:47:59 2025