structure nameHUMAN HOLO-PIC IN THE OPEN STATE
sourceHOMO SAPIENS
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;P-loop containing nucleoside triphosphate hydrolases;
reference complex5iy6_M 5iy6_N 5iy6_P 5iy6_T 5iy6_V
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKKR/YKDH//SNDKATRDSQKNSKNRTMRM/PLNSEDEQELHDGILNRDKG/NVFLFVTNVFPLFVT/KH/L

Estimated binding specificities ?

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# IC=26.401 IC/col=0.754 n_of_columns=35 specificity:   
A |  96   0  96  96  92  96   0  24  24  24  24  24  24  24  24  10   0   0  11   0   3  96  96   3   0   0   0   6  24   0  24   0  24  24   5
C |   0   0   0   0   0   0   0  24  24  24  24  24  24  24  24   6   0  96  10  96   3   0   0  11   0   0   0   6  24   0  24   0  24  24   3
G |   0   0   0   0   0   0  96  24  24  24  24  24  24  24  24  70  96   0  65   0  87   0   0  10   0   0   0   9  24   0  24   0  24  24  85
T |   0  96   0   0   4   0   0  24  24  24  24  24  24  24  24  10   0   0  10   0   3   0   0  72  96  96  96  75  24  96  24  96  24  24   3
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updated Thu Jun 25 05:16:58 2026