structure nameHUMAN HOLO-PIC IN THE CLOSED STATE
(GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyRap30/74 interaction domains;"Winged helix" DNA-binding domain;
sequence familyTranscription initiation factor IIF, beta;
multimeric complexes5iy6_AMPTV 5iy7_ABEMNPTV 5iy8_ABEMNPTV 5iy9_ABEMNPTV 5iya_AMPT 5iyb_ABEMNPT 5iyc_ABEMNPT 5iyd_ABEMNPT 6o9l_7AMNPT 6o9l_ES 7lbm_AMOPTW 7lbm_BEQ 7nvr_7AEMORU 7nvs_AMORU 7nvs_BE 7nvt_AMORU 7nvu_ABEMORU 7nvy_7AMORU 7nvy_BE 7nvz_7AMORU 7nw0_7ABEMORU 7zwd_AMORUbc 7zwd_BE 7zx7_AMORUbc 7zx7_BE 8s51_ABEMORU 8s52_ABEMORU 8s5n_ABEMORU
redundant complexes5iya_T 5iyc_T 6o9l_T 5iy7 5iy8 5iy9 5iyb 5iyd 7lbm 7nvr 7nvs 7nvt 7nvu 7nvy 7nvz 7nw0 7zwd 7zx7 7zx8 8bvw 8byq 8bz1 8s51 8s52 8s5n
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKH

Estimated binding specificities ?

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# IC=2.732 IC/col=0.273 n_of_columns=10 specificity:   
A |  11   0   9  24  24  24  24  24  24   1
C |   9  96  67  24  24  24  24  24  24  67
G |  67   0   9  24  24  24  24  24  24   9
T |   9   0  11  24  24  24  24  24  24  19
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updated Fri Sep 13 19:52:58 2024