structure nameHUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;P-loop containing nucleoside triphosphate hydrolases;
reference complex5iy6_M 5iy6_N 5iy6_P 5iy6_T 5iy6_V
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRTARH/KYRKQIKHK/R/RFNATNTSRNK/EELEDFRIKDW/NVFLFVNVFPLFVT/KIH/L

Estimated binding specificities ?

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# IC=33.563 IC/col=0.541 n_of_columns=62 specificity:   
A |   2   8  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0   0  24   0  78   2  24   0  96   0  24  77   2  24  96  96   0   0  24   0   0   2  24  24  24  24  24  24  24   7   2   3   2   0   0  93   0  93
C |   2   6  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0  96   0  24   0   6  89  24   0   0   0  24   6  89  24   0   0  96   0  24   0  96  89  24  24  24  24  24  24  24  79  89   2   3  96   0   1   0   2
G |  89   5  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0  96  24  96   6   2  24  96   0  96  24   6   3  24   0   0   0  96  24  96   0   3  24  24  24  24  24  24  24   6   3   2   2   0   0   0   0   0
T |   3  77  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  96   0   0  24   0   6   3  24   0   0   0  24   7   2  24   0   0   0   0  24   0   0   2  24  24  24  24  24  24  24   4   2  89  89   0  96   2  96   1
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updated Wed Jul 30 08:59:57 2025