5iy9_ABEMNPTV : 3D-footprint complex

structure name	HUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS)
source	HOMO SAPIENS
experiment	NMR
structural superfamily	Cyclin-like;Zinc beta-ribbon;
reference complex	5iy6_M
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5iy9_A interface=240,823,824,1385,1386, dsacplrtikrvqfgvlspdelkrmsvteggikypetteggrpklgglmdprqgviertgrcqtcagnmtecpghfghielakpvfhvgflvktmkvlrcvcffcskllvdsnnpkikdilakskgqpkkrlthvydlckgkniceggghggcgryqprirrsglelyaewkhvnedsqekkillspervheifkrisdeecfvlgmepryarpewmivtvlpvpplsvrpavvmqgsaRnqddlthkladivkinnqlrrneqngaaahviaedvkllqfhvatmvdnelpglpramqksgrplkslkqrlkgkegrvrgnlmgkrvdfsartvitpdpnlsidqvgvprsiaanmtfaeivtpfnidrlqelvrrgnsqypgakyiirdngdridlrfhpkpsdlhlqtgykverhmcdgdivifnrqptlhkmsmmghrvrilpwstfrlnlsvttpynadfdgdemnlhlpqsletraeiqelamvprmivtpqsnrpvmgivqdtltavrkftkrdvflergevmnllmflstwdgkvpqpailkprplwtgkqifsliipghincirthsthpddedsgpykhispgdtkvvvengelimgilckkslgtsagslvhisylemghditrlfysniqtvinnwllieghtigigdsiadsktyqdiqntikkakqdvieviekahnneleptpgntlrqtfenqvnrilndardktgssaqkslseynnfksmvvsgakgskinisqviavvgqqnvegkripfgfkhrtlphfikddygpesrgfvensylagltptefffhamggreglidtavkTAetgyiqrrliksmesvmvkydatvrnsinqvvqlrygedglagesvefqnlatlkpsnkafekkfrfdytneralrrtlqedlvkdvlsnahiqnelerefermredrevlrvifptgdskvvlpcnllrmiwnaqkifhinprlpsdlhpikvvegvkelskklvivngddplsrqaqenatllfnihlrstlcsrrmaeefrlsgeafdwllgeieskfnqaiahpgemvgalaaqslgepatqmtlntfhyagvsaknvtlgvprlkeliniskkpktpsltvfllgqsardaerakdilcrlehttlrkvtantaiyydpnpqstvvaedqewvnvyyempdfdvarispwllrveldrkhmtdrkltmeqiaekinagfgddlncifnddnaeklvlririmnsdenkmqeeeevvdkmdddvflrciesnmltdmtlqgieqiskvymhlpqtdnkkkiiitedgefkalqewiletdgvslmrvlsekdvdpvrttsndiveiftvlgieavrkalerelyhvisfdgsyvnyrhlallcdtmtcrghlmaitRHgvnrqdtgplmkcsfeetvdvlmeaaahgesdpmkgvsenimlgqlapagtgcfdllldaekckygme > 5iy9_B interface=202,253,407,449,452,480,485,509,806, ydedddeitpdlwqeacwivissyfdekglvrqqldsfdefiqmsvqrivedappidlqaeaqhasgeveeppryllkfeqiylskpthwerdgapspmmpnearlrnltysaplyvditktvikegeeqlqtqhqktfigkipimlrstycllngltdrdlcelnecpldpggyfiingsekvliaqekmatntvyvfakKdskyaytgecrsclenssrptstiwvsmlarggqgakksaigqrivatlpYikqevpiiivfralgfvsdrdilehiiydfedpemmemvkpsldeafviqeqnvalnfigsrgakpgvtkekrikyakevlqkemlphvgvsdfcetkkayflgymvhrlllaalgrrelddrdhygnkrldlagpllaflfrgmfknllkevRiyaqkfidrgkdfnlelaiktriisdglkyslatgnwgdqkKahQaragvsqvlnrltfastlshlrrlnspIgrdgKlakprqlhntlwgmvcpaetpegHavglvknlalmayisvgsqpspilefleewsmenleeispaaiadatkifvngcwvgihkdpeqlmntlrklrrqmdiivsevsmirdirereiriytdagricrpllivekqklllkkrhidqlkereynnyswqdlvasgvveyidtleeetvmlamtpddlqekevaycstythceihpsmilgvcasiipfpdhnqsprntyqsamgkqamgvyitnfhvrmdtlahvlyypqkplvttrsmeylrfrelpaginsivaiasytgynqedsvimnrsavdrgffrsvfyrsyKeqeskkgfdqeevfekptretcqgmrhaiydkldddgliapgvrvsgddviigktvtlpenedelestnrrytkrdcstflrtsetgivdqvmvtlnqegykfckirvrsvripqigdkfasrhgqkgtcgiqyrqedmpftcegitpdiiinphaipsrmtighlieclqgkvsankgeigdatpfndavnvqkisnllsdygyhlrgnevlyngftgrkitsqifigptyyqrlkhmvddkihsrargpiqilnrqpmegrsrdgglrfgemerdcqiahgaaqflrerlfeasdpyqvhvcnlcgimaiantrthtyecrgcrnktqislvrmpyackllfqelmsmsiaprmmsv > 5iy9_E interface= mddeeetyrlwkirktimqlchdrgylvtqdeldqtleefkaqsgdkpsegrprrtdltvlvahnddptdqmfvffpeepkvgiktikvycqrmqeenitralivvqqgmtpsakqslvdmapkyileqflqqellinitehelvpehvvmtkeevtellaryklrenqlpriqagdpvaryfgikrgqvvkiirpsetagRyityrlvq > 5iy9_M interface=47,49,51,54,55,66,100,103,106,110,113, ldalprvtcpnhpdailvedyragdmicpecglvvgdrvidvgsewRtFsNdkATkdpsrvgdsqNpllsdgdlstmigkgtgaasfdefgnskyqnrrTmsSsdRammNafKeittmadrinlprnivdrtnnlfkqvyeqkslkgrandaiasaclyiacrqegvprtfkeicavsriskkeigrcfklilkaletsvdlittgdfmsrfcsnlclpkqvqmaathiarkaveldlvpgrspisvaaaaiymasqasaekrtqkeigdiagvadvtirqsyrliyprapdlfptdfkfdtpvdklpql > 5iy9_N interface= tvpklyrsviedvindvrdiflddgvdeqvlmelktlwenklmgqvEeEpLnsEDdvsdeegqelFdtenvvvcqydkihrsknkwkfhlkdgimnlngRdyIfsKaigDaeW > 5iy9_P interface=15,17,45,60,62,68,105,107,136,137,151,153,159,161, tpasessgivpqlqNiVstvnlgckldlktialrarnaeynpkrFaavimrireprttaLiFssgkmVctgakseeqsrlaarkyarvvqklgfpakfldfkiqNmVgscdvkfpirleglvlthqqfssyepelFPgliyrmikprivlLiFvsgkvVlTgakvraeiyeafeniypilkgfrk > 5iy9_T interface=158,212,213, aergeldltgakqntgvwlvkvpkylsqqwakasgrgevgklriaktqgrtevsftlnedlanehpfvlqsvggqtltvftesssdklslegivvqraecrpaasenymrlkrlqieesskpvrlsqqldkvvttnykpvanhqynieyerkkkedgKraradkqhvldmlfsafekhqyynlkdlvditkqpvvylkeilkeigvqnvkgIHkntwelkpe > 5iy9_V interface=170, ipmdlfdfyeqmdkdeeeeeetqtvsfevkqemieelqkrcihleypllaeydfrndsvnpdinidlkptavlrpyqekslrkmfgngrarsgvivlpcgagkslvgvtaactvrkrclvlgnsavsveqwkaqfkmwstiddsqicrftsdakdkpigcsvaistysmLghttkrsweaervmewlktqewglmildevhtipakmfrrvltivqahcklgltatlvreddkivdlnfligpklyeanwmelqnngyiakvqcaevwcpmspefyreyvaiktkkrillytmnpnkfracqflikfherrndkiivfadnvfalkeyairlnkpyiygptsqgermqilqnfkhnpkintifiskvgdtsfdlpeanvliqisshggsrrqeaqrlgrvlrakkgmvaeeynaffyslvsqdtqemaystkrqrflvdqgysfkvitklagmeeedlafstkeeqqqllqkvla
interface signature	RTARH/KYRKQIKHK/R/RFNATNTSRNK/EELEDFRIKDW/NVFLFVNVFPLFVT/KIH/L

Estimated binding specificities ?

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# IC=33.657 IC/col=0.543 n_of_columns=62

specificity:

A |   3   6  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0   0  24   0  77   2  24   0  96   0  24  77   2  24  96  96   0   0  24   0   0   2  24  24  24  24  24  24  24   6   2   2   2   0   0  93   0  91
C |   2   8  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0  96   0  24   0   7  89  24   0   0   0  24   7  90  24   0   0  96   0  24   0  96  92  24  24  24  24  24  24  24  79  89   2   2  96   0   1   0   2
G |  89   5  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0  96  24  96   6   3  24  96   0  96  24   6   2  24   0   0   0  96  24  96   0   0  24  24  24  24  24  24  24   6   2   2   3   0   0   0   0   0
T |   2  77  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  96   0   0  24   0   6   2  24   0   0   0  24   6   2  24   0   0   0   0  24   0   0   2  24  24  24  24  24  24  24   5   3  90  89   0  96   2  96   3

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updated Sat Dec 14 03:34:40 2024