structure nameHUMAN CORE-PIC IN THE OPEN STATE
sourceHOMO SAPIENS
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;
reference complex5iy6_M 5iy6_N 5iy6_P 5iy6_T
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKKR/YKDH//SNDKATRDSQKNSKNRTMRM/PLNSEDEQELHDGILNRDKG/NVFLFVTNVFPLFVT/KH

Estimated binding specificities ?

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# IC=26.129 IC/col=0.747 n_of_columns=35 specificity:   
A |   2  24  24  11  24   0  24  11   0  96   0   0  96  96   5   0  11   0   0   8  24  24  24  24  24  24  24  24   0   0   2   0   0  96   0
C |  87  24  24  69  24   2  24  11   0   0  96   0   0   0  87   0  72   0  96  64  24  24  24  24  24  24  24  24  96   0   0   0   0   0   0
G |   2  24  24  11  24  94  24  61  96   0   0  96   0   0   2  96   5  96   0  11  24  24  24  24  24  24  24  24   0   0   0   0   0   0   0
T |   5  24  24   5  24   0  24  13   0   0   0   0   0   0   2   0   8   0   0  13  24  24  24  24  24  24  24  24   0  96  94  96  96   0  96
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updated Mon Jan 5 18:16:11 2026