structure nameHUMAN CORE-PIC IN THE INITIAL TRANSCRIBING STATE
sourceHOMO SAPIENS
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;
reference complex5iy6_M 5iy6_N 5iy6_P 5iy6_T
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureMKTR/WYKYKKQIKR//RFSNASNKNRTRNK/EEPLEEFHLGRKDW/NVFLFVTNFPLFVT/KIH

Estimated binding specificities ?

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# IC=32.563 IC/col=0.857 n_of_columns=38 specificity:   
A |   0   0  24   2  96   4   0   4  96   2  24  96   2  11  93  96   0   0   0   5   0   0  24  24  24  24  24  24  24  24   0   0   5   0   0  96   0  81
C |  96   0  24   2   0  88   0   2   0   4  24   0  83  10   0   0  96   0  96   5  96  96  24  24  24  24  24  24  24  24  96   0   5   0   0   0   0   5
G |   0  96  24  90   0   2   3  88   0  88  24   0   6  65   1   0   0  96   0  81   0   0  24  24  24  24  24  24  24  24   0   0   6   0   0   0   0   5
T |   0   0  24   2   0   2  93   2   0   2  24   0   5  10   2   0   0   0   0   5   0   0  24  24  24  24  24  24  24  24   0  96  80  96  96   0  96   5
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updated Thu Jun 25 05:43:48 2026