5iyd_ABEMNPT : 3D-footprint complex

structure name	HUMAN CORE-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS)
source	HOMO SAPIENS
experiment	NMR
structural superfamily	Cyclin-like;Zinc beta-ribbon;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;
reference complex	5iy6_M 5iy6_N 5iy6_P 5iy6_T
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5iyd_A interface=240,823,824,1385,1386, dsacplrtikrvqfgvlspdelkrmsvteggikypetteggrpklgglmdprqgviertgrcqtcagnmtecpghfghielakpvfhvgflvktmkvlrcvcffcskllvdsnnpkikdilakskgqpkkrlthvydlckgkniceggghggcgryqprirrsglelyaewkhvnedsqekkillspervheifkrisdeecfvlgmepryarpewmivtvlpvpplsvrpavvmqgsaRnqddlthkladivkinnqlrrneqngaaahviaedvkllqfhvatmvdnelpglpramqksgrplkslkqrlkgkegrvrgnlmgkrvdfsartvitpdpnlsidqvgvprsiaanmtfaeivtpfnidrlqelvrrgnsqypgakyiirdngdridlrfhpkpsdlhlqtgykverhmcdgdivifnrqptlhkmsmmghrvrilpwstfrlnlsvttpynadfdgdemnlhlpqsletraeiqelamvprmivtpqsnrpvmgivqdtltavrkftkrdvflergevmnllmflstwdgkvpqpailkprplwtgkqifsliipghincirthsthpddedsgpykhispgdtkvvvengelimgilckkslgtsagslvhisylemghditrlfysniqtvinnwllieghtigigdsiadsktyqdiqntikkakqdvieviekahnneleptpgntlrqtfenqvnrilndardktgssaqkslseynnfksmvvsgakgskinisqviavvgqqnvegkripfgfkhrtlphfikddygpesrgfvensylagltptefffhamggreglidtavkTAetgyiqrrliksmesvmvkydatvrnsinqvvqlrygedglagesvefqnlatlkpsnkafekkfrfdytneralrrtlqedlvkdvlsnahiqnelerefermredrevlrvifptgdskvvlpcnllrmiwnaqkifhinprlpsdlhpikvvegvkelskklvivngddplsrqaqenatllfnihlrstlcsrrmaeefrlsgeafdwllgeieskfnqaiahpgemvgalaaqslgepatqmtlntfhyagvsaknvtlgvprlkeliniskkpktpsltvfllgqsardaerakdilcrlehttlrkvtantaiyydpnpqstvvaedqewvnvyyempdfdvarispwllrveldrkhmtdrkltmeqiaekinagfgddlncifnddnaeklvlririmnsdenkmqeeeevvdkmdddvflrciesnmltdmtlqgieqiskvymhlpqtdnkkkiiitedgefkalqewiletdgvslmrvlsekdvdpvrttsndiveiftvlgieavrkalerelyhvisfdgsyvnyrhlallcdtmtcrghlmaitRHgvnrqdtgplmkcsfeetvdvlmeaaahgesdpmkgvsenimlgqlapagtgcfdllldaekckygme > 5iyd_B interface=202,253,407,449,452,480,485,509,806, ydedddeitpdlwqeacwivissyfdekglvrqqldsfdefiqmsvqrivedappidlqaeaqhasgeveeppryllkfeqiylskpthwerdgapspmmpnearlrnltysaplyvditktvikegeeqlqtqhqktfigkipimlrstycllngltdrdlcelnecpldpggyfiingsekvliaqekmatntvyvfakKdskyaytgecrsclenssrptstiwvsmlarggqgakksaigqrivatlpYikqevpiiivfralgfvsdrdilehiiydfedpemmemvkpsldeafviqeqnvalnfigsrgakpgvtkekrikyakevlqkemlphvgvsdfcetkkayflgymvhrlllaalgrrelddrdhygnkrldlagpllaflfrgmfknllkevRiyaqkfidrgkdfnlelaiktriisdglkyslatgnwgdqkKahQaragvsqvlnrltfastlshlrrlnspIgrdgKlakprqlhntlwgmvcpaetpegHavglvknlalmayisvgsqpspilefleewsmenleeispaaiadatkifvngcwvgihkdpeqlmntlrklrrqmdiivsevsmirdirereiriytdagricrpllivekqklllkkrhidqlkereynnyswqdlvasgvveyidtleeetvmlamtpddlqekevaycstythceihpsmilgvcasiipfpdhnqsprntyqsamgkqamgvyitnfhvrmdtlahvlyypqkplvttrsmeylrfrelpaginsivaiasytgynqedsvimnrsavdrgffrsvfyrsyKeqeskkgfdqeevfekptretcqgmrhaiydkldddgliapgvrvsgddviigktvtlpenedelestnrrytkrdcstflrtsetgivdqvmvtlnqegykfckirvrsvripqigdkfasrhgqkgtcgiqyrqedmpftcegitpdiiinphaipsrmtighlieclqgkvsankgeigdatpfndavnvqkisnllsdygyhlrgnevlyngftgrkitsqifigptyyqrlkhmvddkihsrargpiqilnrqpmegrsrdgglrfgemerdcqiahgaaqflrerlfeasdpyqvhvcnlcgimaiantrthtyecrgcrnktqislvrmpyackllfqelmsmsiaprmmsv > 5iyd_E interface= mddeeetyrlwkirktimqlchdrgylvtqdeldqtleefkaqsgdkpsegrprrtdltvlvahnddptdqmfvffpeepkvgiktikvycqrmqeenitralivvqqgmtpsakqslvdmapkyileqflqqellinitehelvpehvvmtkeevtellaryklrenqlpriqagdpvaryfgikrgqvvkiirpsetagRyityrlvq > 5iyd_M interface=47,49,51,54,55,66,100,103,106,110,113, ldalprvtcpnhpdailvedyragdmicpecglvvgdrvidvgsewRtFsNdkATkdpsrvgdsqNpllsdgdlstmigkgtgaasfdefgnskyqnrrTmsSsdRammNafKeittmadrinlprnivdrtnnlfkqvyeqkslkgrandaiasaclyiacrqegvprtfkeicavsriskkeigrcfklilkaletsvdlittgdfmsrfcsnlclpkqvqmaathiarkaveldlvpgrspisvaaaaiymasqasaekrtqkeigdiagvadvtirqsyrliyprapdlfptdfkfdtpvdklpql > 5iyd_N interface= tvpklyrsviedvindvrdiflddgvdeqvlmelktlwenklmgqvEeEpLnsEDdvsdeegqelFdtenvvvcqydkihrsknkwkfhlkdgimnlngRdyIfsKaigDaeW > 5iyd_P interface=15,17,45,60,62,68,105,107,136,137,151,153,159,161, tpasessgivpqlqNiVstvnlgckldlktialrarnaeynpkrFaavimrireprttaLiFssgkmVctgakseeqsrlaarkyarvvqklgfpakfldfkiqNmVgscdvkfpirleglvlthqqfssyepelFPgliyrmikprivlLiFvsgkvVlTgakvraeiyeafeniypilkgfrk > 5iyd_T interface=158,212,213, aergeldltgakqntgvwlvkvpkylsqqwakasgrgevgklriaktqgrtevsftlnedlanehpfvlqsvggqtltvftesssdklslegivvqraecrpaasenymrlkrlqieesskpvrlsqqldkvvttnykpvanhqynieyerkkkedgKraradkqhvldmlfsafekhqyynlkdlvditkqpvvylkeilkeigvqnvkgIHkntwelkpe
interface signature	RTARH/KYRKQIKHK/R/RFNATNTSRNK/EELEDFRIKDW/NVFLFVNVFPLFVT/KIH

Estimated binding specificities ?

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# IC=31.624 IC/col=0.811 n_of_columns=39

specificity:

A |   4  96   2  96  96  88  88   4   9  24  24  24  24  24  24  24   2   0   0  24   0   0   0   0  24   4   5  24   0   0   0  24   2   5   0  24   0   0   0
C |   0   0   2   0   0   2   4   2   5  24  24  24  24  24  24  24   2   0  96  24   0   0   0   0  24   2   5  24   0   0   0  24   2   6   0  24   0   0   0
G |   2   0   2   0   0   2   2  88  77  24  24  24  24  24  24  24  90  96   0  24   0   0   0   0  24   2   5  24   0   0   0  24   4   5   0  24   0   0   0
T |  90   0  90   0   0   4   2   2   5  24  24  24  24  24  24  24   2   0   0  24  96  96  96  96  24  88  81  24  96  96  96  24  88  80  96  24  96  96  96

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updated Tue Sep 10 05:39:08 2024