structure nameHUMAN CORE-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;
reference complex5iy6_M 5iy6_N 5iy6_P 5iy6_T
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRTARH/KYRKQIKHK/R/RFNATNTSRNK/EELEDFRIKDW/NVFLFVNVFPLFVT/KIH

Estimated binding specificities ?

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# IC=31.711 IC/col=0.813 n_of_columns=39 specificity:   
A |   2  96   2  96  96  88  88   2   8  24  24  24  24  24  24  24   2   0   0  24   0   0   0   0  24   2   5  24   0   0   0  24   4   5   0  24   0   0   0
C |   0   0   2   0   0   2   4   2   5  24  24  24  24  24  24  24   4   0  96  24   0   0   0   0  24   2   5  24   0   0   0  24   2   5   0  24   0   0   0
G |   4   0   0   0   0   2   2  90  77  24  24  24  24  24  24  24  88  96   0  24   0   0   0   0  24   4   6  24   0   0   0  24   2   5   0  24   0   0   0
T |  90   0  92   0   0   4   2   2   6  24  24  24  24  24  24  24   2   0   0  24  96  96  96  96  24  88  80  24  96  96  96  24  88  81  96  24  96  96  96
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updated Mon Jan 5 18:27:29 2026