5sva_AZcdfjn : 3D-footprint complex

structure name	MEDIATOR-RNA POLYMERASE II PRE-INITIATION COMPLEX
source	SACCHAROMYCES CEREVISIAE
experiment	NMR
structural superfamily	Cyclin-like;Zinc beta-ribbon;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;
reference complex	5oqj_M 5oqj_Q 5oqj_R 5oqj_U 5sva_n
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5sva_A interface= gqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgsidrnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehnelmrqalaikdskkrfaaiwtlcktkmvcetdvpseddptqlvsrggcgntqptirkdglklvgswkkdratgdadepelrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclpvppppvrpsisfnesqrgeddltfkladilkanisletlehngaphhaieeaesllqfhvatymdndiagqpqalqksgrpvksirarlkgkegrirgnlmgkrvdfsartvisgdpnleldqvgvpksiaktltypevvtpynidrltqlvrngpnehpgakyvirdsgdridlryskragdiqlqygwkverhimdndpvlfnrqpslhkmsmmahrvkvipystfrlnlsvtspynadfdgdemnlhvpqseetraelsqlcavplqivspqsnkpcmgivqdtlcgirkltlrdtfieldqvlnmlywvpdwdgviptpaiikpkplwsgkqilsvaipngihlqrfdegttllspkdngmliidgqiifgvvekktvgssngglihvvtrekgpqvcaklfgniqkvvnfwllhngfstgigdtiadgptmreitetiaeakkkvldvtkeaqanlltakhgmtlresfednvvrflneardkagrlaevnlkdlnnvkqmvmagskgsfiniaqmsacvgqqsvegkriafgfvdrtlphfskddyspeskgfvensylrgltpqefffhamggreglidtavktaetgyiqrrlvkaledimvhydnttrnslgnviqfiygedgmdaahiekqsldtiggsdaafekryrvdllntdhtldpsllesgseilgdlklqvlldeeykqlvkdrkflrevfvdgeanwplpvnirriiqnaqqtfhidhtkpsdltikdivlgvkdlqenllvlrgkneiiqnaqrdavtlfccllrsrlatrrvlqeyrltkqafdwvlsnieaqflrsvvhpgemvgvlaaqsigepatqmtkkvtsgvprlkeilnvaknmktpsltvylepghaadqeqaklirsaiehttlksvtiaseiyydpdprstvipedeeiiqlhfslqqspwllrleldraamndkdltmgqvgerikqtfkndlfviwsedndekliircrvvaeedhmlkkientmlenitlrgveniervvmmkydrkvpsptgeyvkepewvletdgvnlsevmtvpgidptriytnsfidimevlgieagraalykevynviasdgsyvnyrhmallvdvmttqggltsvtrhgfnrsntgalmrcsfeetveilfeagasaelddcrgvsenvilgqmapigtgafdvmideeslvkymp > 5sva_Z interface=166,469, saviggdnereeedddidavhsfeianesvevvkkrcqeidypvleeydfrndhrnpdldidlkpstqirpyqekslskmfgngrarsgiivlpcgagktlvgitaactikksvivlctssvsvmqwrqqflqwctlqpencavftsdnkemfqtesglvvstysMvantrnrshdsqkvmdfltgrewgfiildevhvvpaamfrrvvstiaahaklgltatlvreddkigdlnfligpklyeaianvqcaevwcpmtaefyqeylretarkrmllyimnptkfqacqfliqyherrgdkiivfsdnvyalqeyalkmgkpfiygstpqqermnilqnfqyndqintiflskvgdtsidlpeatcliqisshygsrrqeaqrlgrilrakrrndegfnaffyslvskdtqemyystkrqaflvdqgyafkvithlhgmennlayasprerrellqevlgddadnsvgR > 5sva_c interface= ltcpeckvyppkiverfsegdvvcalcglvlsdklvdtrsewrtfsnddhngddpsrvgeasnplldgnnlstrigkgettdmrftkelnkaqgknvkdnevqaafakitmlcdaaelpkivkdcakeayklchdektlkgksmesimaasiligcrraevartfKeiqslihvktkefgktlnimkni > 5sva_d interface= snaeasrvyeiivesvvnevredfenagideqtlqdlkniwqkkltetkvttfswdnqfndylisedgpdenlmlclydkvtrtkarwkcslkdgvvtinrndytfqkaqveaewv > 5sva_f interface= nefplraipkedlenmrthllkfqskkkinpvtdfhlpvrlhrkdtrnlqfqltragnlrrktrqlkvldenakklrfeefypwvmedgyntwvgsyeagnsdsyvllsveddgsftmipadkvykftarnkyatltideaekrmdkks > 5sva_j interface=9,11,39,40,41,54,56,62,64,99,101,130,131,145,147,153,155, sgivptlqNiVatvtlgcrldlktvalharnaeynpkrFAAvimrirepkttaLiFasgkmVvTgakseddsklasrkyariiqkigfaakftdfkiqNiVgscdvkfpirleglafshgtfssyepelFPgliyrmvkpkivlLiFvsgkiVlTgakqreeiyqafeaiypvlsefrkm > 5sva_n interface= mvatvkrtIrIktqqhilpevppvenfpvrqwsieivlLDDegkeipatifdkViYhlhptFaNpnrtftdppfrieeqgwggfpldisvfllekageRkIphdlnflqesyevehviqiplnkpllteELaksgstdleklafGlTklnedDlVgvvqmvtdnktpemnvtnnveegefiidlyslpegllkslwdyvk
interface signature	/MR/K///NVFAALFVTNVFPLFVT/IILDDVYFNRIELGTDV

Estimated binding specificities ?

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# IC=10.669 IC/col=0.248 n_of_columns=43

specificity:

A |  11  96   9  96   0  96  96   0  67  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0
C |   9   0   9   0   0   0   0   0  11  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0
G |   9   0   9   0   0   0   0   0   9  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  96
T |  67   0  69   0  96   0   0  96   9  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0

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updated Sat Dec 14 06:55:20 2024