structure nameMEDIATOR-RNA POLYMERASE II PRE-INITIATION COMPLEX
sourceSACCHAROMYCES CEREVISIAE
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;P-loop containing nucleoside triphosphate hydrolases;
reference complex5oqj_M 5oqj_O 5oqj_Q 5oqj_R 5oqj_U 5sva_Z 5sva_n
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signature/MR/K///NVFAALFVTNVFPLFVT/IILDDVYFNRIELGTDV

Estimated binding specificities ?

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# IC=10.630 IC/col=0.247 n_of_columns=43 specificity:   
A |   9  96  11  96   0  96  96   0  67  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0
C |   9   0   9   0   0   0   0   0   9  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0
G |  11   0   9   0   0   0   0   0  11  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  96
T |  67   0  67   0  96   0   0  96   9  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0
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updated Mon Jan 5 21:51:35 2026