structure nameMEDIATOR-RNA POLYMERASE II PRE-INITIATION COMPLEX
sourceSACCHAROMYCES CEREVISIAE
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;P-loop containing nucleoside triphosphate hydrolases;
reference complex5oqj_M 5oqj_O 5oqj_Q 5oqj_R 5oqj_U 5sva_Z 5sva_n
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signature/MR/K///NVFAALFVTNVFPLFVT/IILDDVYFNRIELGTDV

Estimated binding specificities ?

readout + contactlogo
# IC=10.748 IC/col=0.250 n_of_columns=43 specificity:   
A |   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   9  96   0   0  96   0  69   0  69
C |  96  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   9   0   0   0   0   0   9   0   9
G |   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   9   0   0   0   0   0   9   0   9
T |   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  69   0  96  96   0  96   9  96   9
scan!

home
updated Thu Jun 25 09:05:37 2026