5tkz_B : 3D-footprint complex

structure name	MEC-8 N-TERMINAL RRM BOUND TO TANDEM GCAC LIGAND (Mec-8 protein)
reference	Mackereth et al. RNA 23 308 2017
source	Caenorhabditis elegans
experiment	X-ray (resolution=1.53, R-factor=0.235)
structural superfamily	RNA-binding domain, RBD;
sequence family	RNA recognition motif aka RRM, RBD, or;
multimeric complexes	5tkz_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5tkz_B interface=4,6,8,33,35,37,44,45,47,49,79,81,83,84,85,87,88, qvrTlFvSglpmdakprelyllfrgargyegaLlKmTskngkpTSpVgFvtflsqqdaqdarkmlqgvrfdpeaaqvlRlElAKSnTKv
interface signature	TFSLKTTSVFREAKSTK

Estimated binding specificities ?

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# IC=6.663 IC/col=1.333 n_of_columns=5

specificity:

A |  96   0   0  96   0
C |   0   0  96   0  96
G |   0  96   0   0   0
T |   0   0   0   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  TAFCSG----------LAKATGTGSGVGFA--------RAECACKCSCTAKC   L                            +--5tkz_B    
                                                                      +---------------1 
  TAFCAG------------RC--------FA----DA--RAEGACRCNCMCAC   L       +----2               +--6dg0_A    
                                                                 !    ! 
  DGICLGWG--------QGKT----KGFGFG------RG----PCNC------   L     +-3    +------------------4y0f_A    
                                                               ! ! 
  ------KTTGYCNGRT------------------------------------   L   +-4 +-----------------------1b3t_A    
                                                             ! ! 
  --------------------------------LG------------------     --5 +------------------------6dgd_B    
                                                             ! 
  ------------------------------RG--------------------   L   +--------------------------3qfq_B

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updated Fri Sep 13 20:29:18 2024