5xp8_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE PROTEIN COMPLEXED WITH A BULGE 4A5 ON THE GUIDE STRAND
reference	Serganov et al. 'Nucleic 45 9149 2017
experiment	X-ray (resolution=3.10, R-factor=0.217)
structural superfamily	Ribonuclease H-like;
sequence family	Piwi domain 502;
multimeric complexes	3hk2_AB 3hvr_AB
reference complex	4ncb_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xp8_A interface=43,46,266,438,439,442,479,603,608,640, nhlgktevflnrfalrplnpeelrpwrlevvldpppgreevyPllAqvarraggvtvrmgdglaswsppevlvlegtlarmgqtyayrlypkgrrpldpkdpgersvlsalarrllqerlrrlegvwveglavyrrehargpgwrvlggavldlwvsdsgafllevdpayrilcemsleawlaqghplpkrvrnaydrrtwellrlgeedpkelplpgglslldyhaskgrlqgreggrvawvadpkdprkpiphltgllvpvltLedlhalslpweerrrrtreiaswigrrlglgtpeavraqayrlsipklmgrravskpadalrvgfyraqetalallrldgaqgwpeflrrallrafgasgaslrlhtlhahpsqglafrealrkakeegvqavlvltppmawedrnrlkalllreglpsqilnvplreeerHRweNallgllakaglqvvalsgaypaelavgfdaggresfRfggaacavggdgghllwtlpeaqageripqevvwdlleetlwafrrkagrlpsrvlllrdgrvpqdefalalealaregiaydlvsvrksgggrvypvqgrladglyvpledktfllltvhrdFrgtpRplklvheagdtplealahqifhltrlypasgFafprlpaplhladrlvkevgrlgirhlkevdreklffv
interface signature	PALHRNRFRF

Estimated binding specificities ?

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# IC=5.518 IC/col=0.394 n_of_columns=14

specificity:

A |   0  24  24  24  24  24  24  24   0  90  16  16  16   0
C |  90  24  24  24  24  24  24  24   0   0  54  53  17  96
G |   5  24  24  24  24  24  24  24   0   6  16  17  10   0
T |   1  24  24  24  24  24  24  24  96   0  10  10  53   0

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updated Mon Dec 18 14:01:39 2023