5xq2_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE PROTEIN COMPLEXED WITH A BULGE 5A6 ON THE GUIDE STRAND (TtAgo D546N)
reference	Serganov et al. 'Nucleic 45 9149 2017
source	Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) / Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
experiment	X-ray (resolution=3.33, R-factor=0.254)
structural superfamily	Ribonuclease H-like;
sequence family	Piwi domain 536;
multimeric complexes	3hk2_AB 3hvr_AB
reference complex	4ncb_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xq2_A interface=40,41,56,264,437,439,440,443,477,480,542,605,609,641, lgktevflnrfalrplnpeelrpwrlevvldpppgreevYPllaqvarraggvtvRmgdglaswsppevlvlegtlarmgqtyayrlypkgrrpldpkdpgersvlsalarrllqerlrrlegvwveglavyrrehargpgwrvlggavldlwvsdsgafllevdpayrilcemsleawlaqghplpkrvrnaydrrtwellrlgeedpkelplpgglslldyhaskgrlqgreggrvawvadpkdprkpiphltgllvpvltLedlheeegslalslpweerrrrtreiaswigrrlglgtpeavraqayrlsipklmgvskpadalrvgfyraqetalallrldgaqgwpeflrrallrafgasgaslrlhtlhahpsqglafrealrkakeegvqavlvltppmawedrnrlkalllreglpsqilnvplreeErHRweNallgllakaglqvvalsgaypaelavgfdaggrEsfRfggaacavggdgghllwtlpeaqageripqevvwdlleetlwafrrkagrlpsrvlllrngRvpqdefalalealaregiaydlvsvrksgggrvypvqgrladglyvpledktfllltvhrdfRgtpRplklvheagdtplealahqifhltrlypasgFafprlpaplhladrlvkevgrlgirhlkevdreklffv
interface signature	YPRLEHRNERRRRF

Estimated binding specificities ?

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# IC=6.294 IC/col=0.450 n_of_columns=14

specificity:

A |   0  24  24   6  24  24  24  75   6  16   0  24  24   0
C |   0  24  24   9  24  24  24  13   6  13   0  24  24   0
G |  96  24  24   6  24  24  24   6  78  61   0  24  24   0
T |   0  24  24  75  24  24  24   2   6   6  96  24  24  96

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updated Mon Dec 18 14:02:18 2023