6erp_ACF : 3D-footprint complex

structure name	STRUCTURE OF THE HUMAN MITOCHONDRIAL TRANSCRIPTION INITIATION COMPLEX AT THE LSP PROMOTER
reference	Morozov et al. Cell 171 1072 2017
source	HOMO SAPIENS
experiment	X-ray (resolution=4.50, R-factor=?)
structural superfamily	HMG-box;DNA/RNA polymerases;S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	3tmm_A 4boc_A 6erp_J
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6erp_A interface=310,421,880,884,894, wakilekdkrtqqmrmqrlkaklqmqlsgqqqrllaffkcclltdqlplahhllvvhhgqrqkrklltldmynavmlgwarqgafkelvyvlfmvkdagltpdllsyaaalqcmgrqdqdagtiercleqmsqeglklqalftavllseedratvlkavhkvkptfslppqlpppvntskllrdvyakdgrvsypklhlplktlqclfekqlhmelasrvcvvsvekptlpskevkharktlktlrdqwekalcralretknrlerevyegrfslypflcllderevvrmllqvlqalpaqgesfttlaRelsartfsrhvvqrqrvsgqvqalqnhyrkylcllasdaevpepclprqywealgapealreqpwplpvqmelgkllaemlvqatqmpcsldrssrlvpvlyhvysfrnvQqigilkphpayvqllekaaeptltfeavdvpmlcpplpwtsphsgafllsptklmrtvegatqhqelletcpptalhgaldaltqlgncawrvngrvldlvlqlfqakgcpqlgvpappseapelahcqkvaremhslraealyrlslaqhlrdrvfwlphnmdfrgrtypcpphfnhlgsdvarallefaqgrplgphgldwlkihlvnltglkkreplrkrlafaeevmddildsadqpltgrkwwmgaeepwqtlaccmevanavrasdpaayvshlpvhqdgscnglqhyaalgrdsvgaasvnlepsdvpqdvysgvaaqvevfrrqdaqrgmrvaqvlegfitrkvvkqtvmtvvygvtryggrlqiekrlrelsdfpqefvweashylvrqvfkslqemfsgtraiqhwltesarlishmgsvvewvtplgvpviqpyrldskvkqiggsiTythNgdisrkpntRkqkngfppnfihsldsshmmltalhcyrkgltfvsvhdcywthaadvsvmnqvcreqfvrlhsepilqdlsrflvkrfcsepqkileasqlketlqavpkpgafdleqvkrstyffs > 6erp_C interface=10,13,15,16,19,35,36,39,115,120,121,124,128,136,137,140, ssvlasspkKpvSsYLrfSkeqlpifkaqnpdakTTelIrriaqrwrelpdskkkiyqdayraewqvykeeisrfkeqltpsqimslekeimdkhlkrkamtkkkeltllgkpkRprsaYNvyVaerFqeakgdsPQekLktvkenwknlsdsekelyiqhakedetryhnemksweeqmievgrkdllrrt > 6erp_F interface=125, kryvtdrrlaetlaqiylghlllecnpgpgiltqalleagakvvalesdktfiphleslgknldgklrvihcdffkldprsggvikppamssrglfknlgieavpwtadiplkvvgmfpsrgekRalwklaydlysctsiykfgrievnmfigekefqklmadpgnpdlyhvlsviwqlaceikvlhmepklyliqmiprqnlftknltpmnyniffhllkhcfgrrsatvidhlrsltpldardilmqigkqedekvvnmhpqdfktlfetierskdcaykwlydet
interface signature	RQTNR/KSYLSTTIRYNVFPQL/R

Estimated binding specificities ?

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# IC=15.960 IC/col=0.469 n_of_columns=34

specificity:

A |   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  67  96   0  96   0  24  24  24  24  24  24  24   0   0  96  96   0  11  67
C |   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24   9   0  96   0   0  24  24  24  24  24  24  24  96  96   0   0  96   9   9
G |  96  24  96  24  24  24  24  24  24  24  24  24  24  24  24   9   0   0   0  96  24  24  24  24  24  24  24   0   0   0   0   0   9  11
T |   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  11   0   0   0   0  24  24  24  24  24  24  24   0   0   0   0   0  67   9

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updated Tue Jan 6 02:55:58 2026