6erp_BGJ : 3D-footprint complex

structure name	STRUCTURE OF THE HUMAN MITOCHONDRIAL TRANSCRIPTION INITIATION COMPLEX AT THE LSP PROMOTER
reference	Morozov et al. Cell 171 1072 2017
source	HOMO SAPIENS
experiment	X-ray (resolution=4.50, R-factor=?)
structural superfamily	DNA/RNA polymerases;S-adenosyl-L-methionine-dependent methyltransferases;HMG-box;
reference complex	4boc_A 6erp_J 7lbx_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6erp_B interface=310,421,861,872,874,886, wakilekdkrtqqmrmqrlkaklqmqlsgqqqrllaffkcclltdqlplahhllvvhhgqrqkrklltldmynavmlgwarqgafkelvyvlfmvkdagltpdllsyaaalqcmgrqdqdagtiercleqmsqeglklqalftavllseedratvlkavhkvkptfslppqlpppvntskllrdvyakdgrvsypklhlplktlqclfekqlhmelasrvcvvsvekptlpskevkharktlktlrdqwekalcralretknrlerevyegrfslypflcllderevvrmllqvlqalpaqgesfttlaRelsartfsrhvvqrqrvsgqvqalqnhyrkylcllasdaevpepclprqywealgapealreqpwplpvqmelgkllaemlvqatqmpcsldrssrlvpvlyhvysfrnvQqigilkphpayvqllekaaeptltfeavdvpmlcpplpwtsphsgafllsptklmrtatqhqelletcpptalhgaldaltqlgncawrvngrvldlvlqlfqakgcpqlgvpappsehcqkvaremhslraealyrlslaqhlrdrvfwlphnmdfrgrtypcpphfnhlgsdvarallefaqgrplgphgldwlkihlvnltglkkreplrkrlafaeevmddildsadqpltgrkwwmgaeepwqtlaccmevanavrasdpaayvshlpvhqdgscnglqhyaalgrdsvgaasvnlepsdvpqdvysgvaaqvevfrrqdaqrgmrvaqvlegfitrkvvkqtvmtvvygvtryggrlqiekrlrelsdfpqefvweashylvrqvfkslqemfsgtraiqhwltesarlishmgsvvewvtplgvpviqpyrlDskvkqiggsiTyThngdisrkpntRkqkngfppnfihsldsshmmltalhcyrkgltfvsvhdcywthaadvsvmnqvcreqfvrlhsepilqdlsrflvkrfcsepqkileasqlketlqavpkpgafdleqvkrstyffs > 6erp_G interface=10,13,15,16,19,23,35,36,39,115,120,121,124,128,136,137,140, ssvlasspkKpvSsYLrfSkeqLpifkaqnpdakTTelIrriaqrwrelpdskkkiyqdayraewqvykeeisrfkeqltpsqimslekeimdkhlkrkamtkkkeltllgkpkRprsaYNvyVaerFqeakgdsPQekLktvkenwknlsdsekelyiqhakedetryhnemksweeqmievgrkdllrrt > 6erp_J interface=125, kryvtdrrlaetlaqiylghlllecnpgpgiltqalleagakvvalesdktfiphleslgknldgklrvihcdffkldprsggvikppamssrglfknlgieavpwtadiplkvvgmfpsrgekRalwklaydlysctsiykfgrievnmfigekefqklmadpgnpdlyhvlsviwqlaceikvlhmepklyliqmiprqnlftknltpmnyniffhllkhcfgrrsatvidhlrsltpldardilmqigkqedekvvnmhpqdfktlfetierskdcaykwlydet
interface signature	RQDTTR/KSYLSLTTIRYNVFPQL/R

Estimated binding specificities ?

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# IC=15.960 IC/col=0.469 n_of_columns=34

specificity:

A |  67   0   0   0   0   0  24  24  24  24  24  24  24   0   0   0   0   9  24  24  24  24  24  24  24  24  24  24  24  24   0  24   0   9
C |  11   0   0   0   0   0  24  24  24  24  24  24  24  96   0   0   0  11  24  24  24  24  24  24  24  24  24  24  24  24  96  24   0   9
G |   9  96   0   0  96  96  24  24  24  24  24  24  24   0   0  96   0   9  24  24  24  24  24  24  24  24  24  24  24  24   0  24   0  67
T |   9   0  96  96   0   0  24  24  24  24  24  24  24   0  96   0  96  67  24  24  24  24  24  24  24  24  24  24  24  24   0  24  96  11

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updated Sat Dec 14 11:26:56 2024