6erq_ACF : 3D-footprint complex

structure name	STRUCTURE OF THE HUMAN MITOCHONDRIAL TRANSCRIPTION INITIATION COMPLEX AT THE HSP PROMOTER
reference	Morozov et al. Cell 171 1072 2017
source	HOMO SAPIENS
experiment	X-ray (resolution=4.50, R-factor=?)
structural superfamily	HMG-box;DNA/RNA polymerases;S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	3tmm_A 4boc_A 6erp_J
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6erq_A interface=310,420,421,479,880,882,884,894, wakilekdkrtqqmrmqrlkaklqmqlsgqqqrllaffkcclltdqlplahhllvvhhgqrqkrklltldmynavmlgwarqgafkelvyvlfmvkdagltpdllsyaaalqcmgrqdqdagtiercleqmsqeglklqalftavllseedratvlkavhkvkptfslppqlpppvntskllrdvyakdgrvsypklhlplktlqclfekqlhmelasrvcvvsvekptlpskevkharktlktlrdqwekalcralretknrlerevyegrfslypflcllderevvrmllqvlqalpaqgesfttlaRelsartfsrhvvqrqrvsgqvqalqnhyrkylcllasdaevpepclprqywealgapealreqpwplpvqmelgkllaemlvqatqmpcsldrssrlvpvlyhvysfrnVQqigilkphpayvqllekaaeptltfeavdvpmlcpplpwtsphsgafllsptklmrtVegatqhqelletcpptalhgaldaltqlgncawrvngrvldlvlqlfqakgcpqlgvpappseapelahcqkvaremhslraealyrlslaqhlrdrvfwlphnmdfrgrtypcpphfnhlgsdvarallefaqgrplgphgldwlkihlvnltglkkreplrkrlafaeevmddildsadqpltgrkwwmgaeepwqtlaccmevanavrasdpaayvshlpvhqdgscnglqhyaalgrdsvgaasvnlepsdvpqdvysgvaaqvevfrrqdaqrgmrvaqvlegfitrkvvkqtvmtvvygvtryggrlqiekrlrelsdfpqefvweashylvrqvfkslqemfsgtraiqhwltesarlishmgsvvewvtplgvpviqpyrldskvkqiggsiTyThNgdisrkpntRkqkngfppnfihsldsshmmltalhcyrkgltfvsvhdcywthaadvsvmnqvcreqfvrlhsepilqdlsrflvkrfcsepqkileasqlketlqavpkpgafdleqvkrstyffs > 6erq_C interface=10,13,15,16,19,35,36,39,115,120,121,124,136,137,140, ssvlasspkKpvSsYLrfSkeqlpifkaqnpdakTTelIrriaqrwrelpdskkkiyqdayraewqvykeeisrfkeqltpsqimslekeimdkhlkrkamtkkkeltllgkpkRprsaYNvyVaerfqeakgdsPQekLktvkenwknlsdsekelyiqhakedetryhnemksweeqmievgrkdllrrt > 6erq_F interface=125, kryvtdrrlaetlaqiylghlllecnpgpgiltqalleagakvvalesdktfiphleslgknldgklrvihcdffkldprsggvikppamssrglfknlgieavpwtadiplkvvgmfpsrgekRalwklaydlysctsiykfgrievnmfigekefqklmadpgnpdlyhvlsviwqlaceikvlhmepklyliqmiprqnlftknltpmnyniffhllkhcfgrrsatvidhlrsltpldardilmqigkqedekvvnmhpqdfktlfetierskdcaykwlydet
interface signature	RVQVTTNR/KSYLSTTIRYNVPQL/R

Estimated binding specificities ?

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# IC=18.285 IC/col=0.538 n_of_columns=34

specificity:

A |   0   0   0  24   7  24  24  24  24  24  24  24  24  24  24   9   0   0   0  96  24  24  24  24  24  24  24  96   0   0  96   0   7   7
C |   0   0   0  24   7  24  24  24  24  24  24  24  24  24  24   7   0   0   0   0  24  24  24  24  24  24  24   0   0  96   0   0  73   7
G |  96  96   0  24   7  24  24  24  24  24  24  24  24  24  24  73  96  96   0   0  24  24  24  24  24  24  24   0  96   0   0  96   7  73
T |   0   0  96  24  75  24  24  24  24  24  24  24  24  24  24   7   0   0  96   0  24  24  24  24  24  24  24   0   0   0   0   0   9   9

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updated Tue Jan 6 02:59:08 2026