6erq_ACF : 3D-footprint complex

structure name	STRUCTURE OF THE HUMAN MITOCHONDRIAL TRANSCRIPTION INITIATION COMPLEX AT THE HSP PROMOTER
reference	Morozov et al. Cell 171 1072 2017
source	HOMO SAPIENS
experiment	X-ray (resolution=4.50, R-factor=?)
structural superfamily	DNA/RNA polymerases;S-adenosyl-L-methionine-dependent methyltransferases;HMG-box;
reference complex	4boc_A 6erp_J 7lbx_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6erq_A interface=310,420,421,479,880,882,884,894, wakilekdkrtqqmrmqrlkaklqmqlsgqqqrllaffkcclltdqlplahhllvvhhgqrqkrklltldmynavmlgwarqgafkelvyvlfmvkdagltpdllsyaaalqcmgrqdqdagtiercleqmsqeglklqalftavllseedratvlkavhkvkptfslppqlpppvntskllrdvyakdgrvsypklhlplktlqclfekqlhmelasrvcvvsvekptlpskevkharktlktlrdqwekalcralretknrlerevyegrfslypflcllderevvrmllqvlqalpaqgesfttlaRelsartfsrhvvqrqrvsgqvqalqnhyrkylcllasdaevpepclprqywealgapealreqpwplpvqmelgkllaemlvqatqmpcsldrssrlvpvlyhvysfrnVQqigilkphpayvqllekaaeptltfeavdvpmlcpplpwtsphsgafllsptklmrtVegatqhqelletcpptalhgaldaltqlgncawrvngrvldlvlqlfqakgcpqlgvpappseapelahcqkvaremhslraealyrlslaqhlrdrvfwlphnmdfrgrtypcpphfnhlgsdvarallefaqgrplgphgldwlkihlvnltglkkreplrkrlafaeevmddildsadqpltgrkwwmgaeepwqtlaccmevanavrasdpaayvshlpvhqdgscnglqhyaalgrdsvgaasvnlepsdvpqdvysgvaaqvevfrrqdaqrgmrvaqvlegfitrkvvkqtvmtvvygvtryggrlqiekrlrelsdfpqefvweashylvrqvfkslqemfsgtraiqhwltesarlishmgsvvewvtplgvpviqpyrldskvkqiggsiTyThNgdisrkpntRkqkngfppnfihsldsshmmltalhcyrkgltfvsvhdcywthaadvsvmnqvcreqfvrlhsepilqdlsrflvkrfcsepqkileasqlketlqavpkpgafdleqvkrstyffs > 6erq_C interface=10,13,15,16,19,35,36,39,115,120,121,124,136,137,140, ssvlasspkKpvSsYLrfSkeqlpifkaqnpdakTTelIrriaqrwrelpdskkkiyqdayraewqvykeeisrfkeqltpsqimslekeimdkhlkrkamtkkkeltllgkpkRprsaYNvyVaerfqeakgdsPQekLktvkenwknlsdsekelyiqhakedetryhnemksweeqmievgrkdllrrt > 6erq_F interface=125, kryvtdrrlaetlaqiylghlllecnpgpgiltqalleagakvvalesdktfiphleslgknldgklrvihcdffkldprsggvikppamssrglfknlgieavpwtadiplkvvgmfpsrgekRalwklaydlysctsiykfgrievnmfigekefqklmadpgnpdlyhvlsviwqlaceikvlhmepklyliqmiprqnlftknltpmnyniffhllkhcfgrrsatvidhlrsltpldardilmqigkqedekvvnmhpqdfktlfetierskdcaykwlydet
interface signature	RVQVTTNR/KSYLSTTIRYNVPQL/R

Estimated binding specificities ?

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# IC=18.240 IC/col=0.536 n_of_columns=34

specificity:

A |   9   7   0   0   0   0   0  24  24  24  24  24  24  24   0  96   0   0   7  24  24  24  24  24  24  24  24  24  24  73  24  96   0  96
C |  73   7  96   0   0  96   0  24  24  24  24  24  24  24   0   0  96  96  73  24  24  24  24  24  24  24  24  24  24   7  24   0   0   0
G |   7  73   0   0  96   0   0  24  24  24  24  24  24  24   0   0   0   0   7  24  24  24  24  24  24  24  24  24  24   7  24   0   0   0
T |   7   9   0  96   0   0  96  24  24  24  24  24  24  24  96   0   0   0   9  24  24  24  24  24  24  24  24  24  24   9  24   0  96   0

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updated Sat Dec 14 11:28:12 2024