6erq_BGJ : 3D-footprint complex

structure name	STRUCTURE OF THE HUMAN MITOCHONDRIAL TRANSCRIPTION INITIATION COMPLEX AT THE HSP PROMOTER
reference	Morozov et al. Cell 171 1072 2017
source	HOMO SAPIENS
experiment	X-ray (resolution=4.50, R-factor=?)
structural superfamily	DNA/RNA polymerases;S-adenosyl-L-methionine-dependent methyltransferases;HMG-box;
reference complex	4boc_A 6erp_J 7lbx_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6erq_B interface=310,420,421,860,871,873,874,875,885, wakilekdkrtqqmrmqrlkaklqmqlsgqqqrllaffkcclltdqlplahhllvvhhgqrqkrklltldmynavmlgwarqgafkelvyvlfmvkdagltpdllsyaaalqcmgrqdqdagtiercleqmsqeglklqalftavllseedratvlkavhkvkptfslppqlpppvntskllrdvyakdgrvsypklhlplktlqclfekqlhmelasrvcvvsvekptlpskevkharktlktlrdqwekalcralretknrlerevyegrfslypflcllderevvrmllqvlqalpaqgesfttlaRelsartfsrhvvqrqrvsgqvqalqnhyrkylcllasdaevpepclprqywealgapealreqpwplpvqmelgkllaemlvqatqmpcsldrssrlvpvlyhvysfrnVQqigilkphpayvqllekaaeptltfeavdvpmlcpplpwtsphsgafllsptklmratqhqelletcpptalhgaldaltqlgncawrvngrvldlvlqlfqakgcpqlgvpappsehcqkvaremhslraealyrlslaqhlrdrvfwlphnmdfrgrtypcpphfnhlgsdvarallefaqgrplgphgldwlkihlvnltglkkreplrkrlafaeevmddildsadqpltgrkwwmgaeepwqtlaccmevanavrasdpaayvshlpvhqdgscnglqhyaalgrdsvgaasvnlepsdvpqdvysgvaaqvevfrrqdaqrgmrvaqvlegfitrkvvkqtvmtvvygvtryggrlqiekrlrelsdfpqefvweashylvrqvfkslqemfsgtraiqhwltesarlishmgsvvewvtplgvpviqpyrlDskvkqiggsiTyTHNgdisrkpntRkqkngfppnfihsldsshmmltalhcyrkgltfvsvhdcywthaadvsvmnqvcreqfvrlhsepilqdlsrflvkrfcsepqkileasqlketlqavpkpgafdleqvkrstyffs > 6erq_G interface=10,13,15,16,19,23,35,36,39,115,120,121,124,128,136,137,140, ssvlasspkKpvSsYLrfSkeqLpifkaqnpdakTTelIrriaqrwrelpdskkkiyqdayraewqvykeeisrfkeqltpsqimslekeimdkhlkrkamtkkkeltllgkpkRprsaYNvyVaerFqeakgdsPQekLktvkenwknlsdsekelyiqhakedetryhnemksweeqmievgrkdllrrt > 6erq_J interface=124,125, kryvtdrrlaetlaqiylghlllecnpgpgiltqalleagakvvalesdktfiphleslgknldgklrvihcdffkldprsggvikppamssrglfknlgieavpwtadiplkvvgmfpsrgeKRalwklaydlysctsiykfgrievnmfigekefqklmadpgnpdlyhvlsviwqlaceikvlhmepklyliqmiprqnlftknltpmnyniffhllkhcfgrrsatvidhlrsltpldardilmqigkqedekvvnmhpqdfktlfetierskdcaykwlydet
interface signature	RVQDTTHNR/KSYLSLTTIRYNVFPQL/KR

Estimated binding specificities ?

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# IC=16.740 IC/col=0.492 n_of_columns=34

specificity:

A |   6   0   0   0   0   6  24  24  24  24  24  24  24   0  96   0   0   6  24  24  24  24  24  24  24  24  24  24  24  24  96   6  96   6
C |   6  96   0   0  96   6  24  24  24  24  24  24  24   0   0  96  96  78  24  24  24  24  24  24  24  24  24  24  24  24   0   6   0   6
G |  78   0   0  96   0   6  24  24  24  24  24  24  24   0   0   0   0   6  24  24  24  24  24  24  24  24  24  24  24  24   0   6   0  78
T |   6   0  96   0   0  78  24  24  24  24  24  24  24  96   0   0   0   6  24  24  24  24  24  24  24  24  24  24  24  24   0  78   0   6

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updated Sat Dec 14 11:29:28 2024