6fb5_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TAILORED I-CREI HOMING ENDONUCLEASE PROTEIN (3115 VARIANT) IN COMPLEX WITH AN ALTERED VERSION OF ITS TARGET DNA (HAEMOGLOBIN BETA SUBUNIT GENE) AT 5NNN REGION IN THE PRESENCE OF MAGNESIUM
reference	Molina et al. 'Sci 8 10286 2018
source	CHLAMYDOMONAS REINHARDTII
experiment	X-ray (resolution=2.20, R-factor=?)
structural superfamily	Homing endonucleases;
reference complex	2vbo_A 6fb0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fb5_A interface=21,23,25,27,29,31,37,39,43,45,65,67,69,72,74,76,139, ntkynkefllylagfvdsdgSiIaQiKpNqSvkfkhRlQltfDvTqktqrrwfldklvdeigvgYvAdSgsVsKyRlseikplhnfltqlqpflklkqkqanlvlkiieqlpsakespdkflevctwvdqiaalndskTrkttsetvravlds > 6fb5_B interface=21,23,25,27,31,37,43,45,67,69,71,72,74,76,138,139, ntkynkefllylagfvdgdgSiIaQiKpnqSgkfkhKlsltfKvTqktqrrwfldklvdeigvgyvYdSgSVsNyYlseikplhnfltqlqpflklkqkqanlvlkiieqlpsakespdkflevctwvdqvaalndsKTrkttsetvravldsl
interface signature	SIQKNSRQDTYASVKRT/SIQKSKKTYSSVNYKT

Estimated binding specificities ?

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# IC=19.133 IC/col=0.870 n_of_columns=22

specificity:

A |   4  24  70   0  24   0   0   0   7   2   5   9  24  24  78   0   0  96   0  90   0  92
C |   5  24  15   0  24  96   0   0  10  10  90  60  24  24   0   1   0   0   0   0  96   2
G |   2  24   5  96  24   0   0   0  73   2   1  10  24  24  15  93  96   0  96   0   0   2
T |  85  24   6   0  24   0  96  96   6  82   0  17  24  24   3   2   0   0   0   6   0   0

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updated Tue Jan 6 03:41:14 2026