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structure nameCRYSTAL STRUCTURE OF A TAILORED I-CREI HOMING ENDONUCLEASE PROTEIN (3115 VARIANT) IN COMPLEX WITH AN ALTERED VERSION OF ITS TARGET DNA (HAEMOGLOBIN BETA SUBUNIT GENE) AT 5NNN REGION IN THE PRESENCE OF MAGNESIUM
referenceMolina et al. 'Sci 8 10286 2018
sourceCHLAMYDOMONAS REINHARDTII
experimentX-ray (resolution=2.20, R-factor=?)
structural superfamilyHoming endonucleases;
reference complex6fb0_A 6fb0_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQKNSRQDTYASVKRT/SIQKSKKTYSSVNYKT

Estimated binding specificities ?

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# IC=19.429 IC/col=0.883 n_of_columns=22 specificity:   
A |   2  24  76   0  24   0   0   0   7   2   3   5  24  24  76   0   0  96   0  88   0  90
C |   2  24  10   0  24  96   0   0  10   8  93  68  24  24   2   1   0   0   0   0  96   2
G |   2  24   5  96  24   0   0   0  74   4   0  10  24  24  13  93  96   0  96   0   0   2
T |  90  24   5   0  24   0  96  96   5  82   0  13  24  24   5   2   0   0   0   8   0   2
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updated Tue Sep 10 13:07:42 2024