6fb5_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TAILORED I-CREI HOMING ENDONUCLEASE PROTEIN (3115 VARIANT) IN COMPLEX WITH AN ALTERED VERSION OF ITS TARGET DNA (HAEMOGLOBIN BETA SUBUNIT GENE) AT 5NNN REGION IN THE PRESENCE OF MAGNESIUM
reference	Molina et al. 'Sci 8 10286 2018
experiment	X-ray (resolution=2.20, R-factor=0.191)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
multimeric complexes	6fb0_AB 6fb5_AB
reference complex	6fb0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fb5_B interface=21,23,25,27,31,37,43,45,67,69,71,72,74,76,138,139, ntkynkefllylagfvdgdgSiIaQiKpnqSgkfkhKlsltfKvTqktqrrwfldklvdeigvgyvYdSgSVsNyYlseikplhnfltqlqpflklkqkqanlvlkiieqlpsakespdkflevctwvdqvaalndsKTrkttsetvravldsl
interface signature	SIQKSKKTYSSVNYKT

Estimated binding specificities ?

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# IC=8.622 IC/col=0.784 n_of_columns=11

specificity:

A |   0  72  12  96  96   0  24   0  12  24  84
C |   0   6  66   0   0   0  24  96  12  24   6
G |  90  12  12   0   0  96  24   0  12  24   6
T |   6   6   6   0   0   0  24   0  60  24   0

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updated Fri Jan 9 06:14:02 2026