interface graph thumbnail
legend  pdf

structure nameSTRUCTURAL BASIS OF NR4A1 BOUND TO THE HUMAN PITUITARY PROOPIOMELANOCORTIN GENE PROMOTER
(NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1)
referenceJiang et al. Biochem.Biophys.Res.Commun. 523 1 2020
sourceHOMO SAPIENS
experimentX-ray (resolution=3.12, R-factor=0.212)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes6lc1_AD
reference complex1cit_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureCYEKKRRR

Estimated binding specificities ?

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# IC=8.936 IC/col=0.894 n_of_columns=10 specificity:   
A |   0   0  24   0  96   0   8  16  96   8
C |   0   0  24   0   0   0  16  16   0  72
G |   0  96  24   0   0   0  16  16   0   8
T |  96   0  24  96   0  96  56  48   0   8
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updated Sun Jun 28 17:39:24 2026