interface graph thumbnail
legend  pdf

structure nameSTRUCTURAL BASIS OF NR4A1 BOUND TO THE HUMAN PITUITARY PROOPIOMELANOCORTIN GENE PROMOTER
(NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1)
referenceJiang et al. Biochem.Biophys.Res.Commun. 523 1 2020
sourceHOMO SAPIENS
experimentX-ray (resolution=3.12, R-factor=0.212)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes6l6l_AB 6l6q_AB 6lc1_AD
reference complex6l6q_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureCYEKKRRR

Estimated binding specificities ?

readout + contactlogo
# IC=9.295 IC/col=0.929 n_of_columns=10 specificity:   
A |   0   0  24   0  96   0   0  16  96   8
C |   0   0  24   0   0   0  16   8   0  72
G |   0  96  24   0   0   0  16  16   0   8
T |  96   0  24  96   0  96  64  56   0   8
scan!

home
updated Fri Sep 13 00:44:58 2024