interface graph thumbnail
legend  pdf

structure nameSTRUCTURAL BASIS OF NR4A1 BOUND TO THE HUMAN PITUITARY PROOPIOMELANOCORTIN GENE PROMOTER
(NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1)
referenceJiang et al. Biochem.Biophys.Res.Commun. 523 1 2020
sourceHOMO SAPIENS
experimentX-ray (resolution=3.12, R-factor=0.212)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes6l6l_AB 6l6q_AB 6lc1_AD
reference complex6l6q_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureCYEKKRRR

Estimated binding specificities ?

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# IC=8.004 IC/col=0.800 n_of_columns=10 specificity:   
A |  11   0  67  24  96   0  96  24   9  96
C |   9   0   9  24   0   0   0  24  69   0
G |  67   0   9  24   0   0   0  24   9   0
T |   9  96  11  24   0  96   0  24   9   0
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updated Mon Dec 18 16:37:04 2023