6vg8_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE DNA BINDING DOMAINS OF HUMAN FLI1 AND RUNX2 IN COMPLEX WITH 16-MER DNA CAGAGGATGTGGCTTC
reference	Tsodikov et al. Structure 29 404 2021
source	HOMO SAPIENS
experiment	X-ray (resolution=4.31, R-factor=?)
structural superfamily	p53-like transcription factors;
reference complex	6vg8_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6vg8_A interface=60,63,66,67, mpgsgqiqlwqfllellsdsanascitwegtngefkmtdpdevarrwgerkskpnmnydKlsRalRYyydknimtkvhgkryaykfdfhgiaqalq > 6vg8_D interface=21,83,111,112,115,118, aelvrtdspnflcsvlpshwRcnktlpvafkvvalgevpdgtvvtvmagndenysaelrnasavmknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikvtVDgpRepRrh
interface signature	KRRY/RRVDRR

Estimated binding specificities ?

readout + contact

# IC=9.159 IC/col=0.916 n_of_columns=10

specificity:

A |   0   0  96   0   0   0  11   0  24  19
C |   0   8   0   0   0   9   8   0  24   8
G |  96  71   0   0  96   0  69  96  24   8
T |   0  17   0  96   0  87   8   0  24  61

scan!

home
updated Sat Dec 14 21:51:50 2024