6vg8_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE DNA BINDING DOMAINS OF HUMAN FLI1 AND RUNX2 IN COMPLEX WITH 16-MER DNA CAGAGGATGTGGCTTC
reference	Tsodikov et al. Structure 29 404 2021
source	HOMO SAPIENS
experiment	X-ray (resolution=4.31, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;p53-like transcription factors;
reference complex	5jvt_A 6vgd_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6vg8_A interface=60,63,66,67, mpgsgqiqlwqfllellsdsanascitwegtngefkmtdpdevarrwgerkskpnmnydKlsRalRYyydknimtkvhgkryaykfdfhgiaqalq > 6vg8_D interface=21,83,111,112,115,118, aelvrtdspnflcsvlpshwRcnktlpvafkvvalgevpdgtvvtvmagndenysaelrnasavmknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikvtVDgpRepRrh
interface signature	KRRY/RRVDRR

Estimated binding specificities ?

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# IC=11.586 IC/col=0.965 n_of_columns=12

specificity:

A |  15  72  15   0   3  96   0  96   0  11   0  15
C |  13  11  13  96  88   0  96   0   0  84  96   7
G |   3   7  57   0   3   0   0   0   0   1   0   9
T |  65   6  11   0   2   0   0   0  96   0   0  65

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updated Fri Jun 26 01:34:23 2026