interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE DNA BINDING DOMAINS OF HUMAN FLI1 AND RUNX2 IN COMPLEX WITH 16-MER DNA CAGAGGATGTGGCTTC
referenceTsodikov et al. Structure 29 404 2021
sourceHOMO SAPIENS
experimentX-ray (resolution=4.31, R-factor=?)
structural superfamily"Winged helix" DNA-binding domain;p53-like transcription factors;
reference complex4iri_A 6vg8_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRRY/RRVDRR

Estimated binding specificities ?

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# IC=7.626 IC/col=0.953 n_of_columns=8 specificity:   
A |   0   6  78   0  82   6   6   0
C |  96  78   6  96   2   8  75  96
G |   0   6   6   0   6   0   6   0
T |   0   6   6   0   6  82   9   0
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updated Tue Sep 10 22:05:45 2024