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structure nameCRYSTAL STRUCTURE OF THE DNA BINDING DOMAIN OF TRANSCRIPTION FACTOR FLI1 IN COMPLEX WITH AN 11-MER DNA GACCGGAAGTG
(Friend leukemia integration 1 transcription factor)
referenceTsodikov et al. 'Nucleic 44 8990 2016
sourceHomo sapiens
experimentX-ray (resolution=3.10, R-factor=0.196)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes5jvt_AD 6vg8_AD 6vgd_AD
redundant complexes6vg2_D 6vg8 6vgd
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDRRY

Estimated binding specificities ?

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# IC=4.638 IC/col=0.928 n_of_columns=5 specificity:   
A |  16   0   0   0  16
C |  16   0  96  96   0
G |  16   0   0   0  64
T |  48  96   0   0  16
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------------DCKT--RG--RGYA----KA   L                               +5jvt_A    
                                                      +--------------4 
  ------------DCKT--RGATRCYA------   L                !              ! +5e8i_D    
                                                      !              +-1 
  --------------KT--RG--RAYA------   L                !                +6vge_A    
                                                    +-8 
  ------------DCKT--RGSTRGYA------   L              ! !               +4bnc_A    
                                                    ! !   +-----------2 
  --------------KT--RG--RGYA------   L              ! +---6           +3wts_C    
                                                  +-9     ! 
  ------------------TT--CT--NGKG--   L            ! !     +-----------7oot_B    
                                                  ! ! 
  --------------KT--RG--RGYA------   L         +-10 !   +-------------4lg0_B    
                                               !  ! +---7 
  NC----------------TT--CT--NGKG--   L         !  !     +-------------7rh2_B    
                                            +-11  !  
  ----RC--------------------------          !  !  +------------------7cow_T    
                                         +-12  !  
  ------LTNTHG--RTYTPT------------   L   !  !  +---------------------6qil_A    
                                         !  !  
  --RC----------------------------       !  +----------------------6l9z_S    
                                       -13  
  ------------DCKT--RG--RGYA------   L   !                        +1dux_F    
                                         !             +----------3 
  ------------ECKT--RGATRGNT------   L   +-------------5          +1pue_E    
                                                       ! 
  --------------------NTCT--NGST--   L                 +----------1if1_B    
                                       

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updated Thu Dec 22 21:47:05 2022