6vgd_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE DNA BINDING DOMAIN (DBD) OF HUMAN FLI1 AND THE COMPLEX OF THE DBD OF HUMAN RUNX2 WITH CORE BINDING FACTOR BETA (CBFB), IN COMPLEX WITH 16MER DNA CAGAGGATGTGGCTTC
reference	Tsodikov et al. Structure 29 404 2021
source	HOMO SAPIENS
experiment	X-ray (resolution=4.20, R-factor=?)
structural superfamily	p53-like transcription factors;
reference complex	6vgd_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6vgd_A interface=63,66,67, mpgsgqiqlwqfllellsdsanascitwegtngefkmtdpdevarrwgerkskpnmnydklsRalRYyydknimtkvhgkryaykfdfhgiaqalqph > 6vgd_D interface=21,83,111,112,115, aelvrtdspnflcsvlpshwRcnktlpvafkvvalgevpdgtvvtvmagndenysaelrnasavmknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikvtVDgpRep
interface signature	RRY/RRVDR

Estimated binding specificities ?

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# IC=11.571 IC/col=1.052 n_of_columns=11

specificity:

A |  96   0   0   0   0   0   0   0  24  19   0
C |   0   0   0   0   0   0   0   0  24  19   0
G |   0  96  96   0  96   0  96  96  24  19  19
T |   0   0   0  96   0  96   0   0  24  39  77

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updated Sat Dec 14 21:51:58 2024