6xwg_CD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN RXR/RAR DNA-BINDING DOMAIN HETERODIMER BOUND TO THE HUMAN RARB2 DR5 RESPONSE ELEMENT
reference	Poussin-Courmontagne et al. 'Nucleic 48 9969 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1dsz_A 6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6xwg_C interface=22,25,29,30, khicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeerq > 6xwg_D interface=25,28,32,33, priykpcfvcqdkssgyhygvsacEgcKgffRRsiqknmvytchrdknciinkvtrnrcqycrlqkcfevgmskesvrnd
interface signature	EKKR/EKRR

Estimated binding specificities ?

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# IC=11.284 IC/col=0.705 n_of_columns=16

specificity:

A |   0  12  76  96   0  12  24  24  24  24  24   0   0  96  96   6
C |   0  12   6   0  96   6  24  24  24  24  24   0   0   0   0  76
G |   0  57   8   0   0  12  24  24  24  24  24   0  96   0   0   8
T |  96  15   6   0   0  66  24  24  24  24  24  96   0   0   0   6

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updated Tue Jan 6 18:32:00 2026