6zmn_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE SMAD3-SMAD5 MH1 DOMAIN CHIMERA BOUND TO THE GGCGC SITE (Mothers against decapentaplegic homolog 3)
reference	Macias et al. 'Comput 19 632 2021
source	Homo sapiens
experiment	X-ray (resolution=2.33, R-factor=0.212)
structural superfamily	SMAD MH1 domain;
sequence family	MH1 domain;
multimeric complexes	1mhd_AB 1ozj_AB
reference complex	5od6_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6zmn_B interface=61,63,65,70, gpavkrllgwkqgdeeekwcekavkslvkklkktgqldelekaittqnvntkcitiprslDgRlQvshrKglphviycrlwrwpdlhshhelramelcefafnmkkdevcvnpyhyqrv
interface signature	DRQK

Estimated binding specificities ?

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# IC=2.635 IC/col=0.659 n_of_columns=4

specificity:

A |   9   9  11   0
C |  67  11  67  96
G |   9  67   9   0
T |  11   9   9   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --RGQAHTKG   L     +-----------------------------5x6g_A    
                   +-2 
  --RGQA--KG   L   ! +-----------------------------3kmp_A    
                 --3 
  DCRGQC--KG   L   !                             +6zmn_B    
                   +-----------------------------1 
  DCRGQC--KG   L                                 +6fzt_A

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updated Fri Sep 13 03:27:36 2024