7lvv_B : 3D-footprint complex

structure name	CRYOEM STRUCTURE DRDV-DNA COMPLEX (SITE-SPECIFIC DNA-METHYLTRANSFERASE ADENINE-SPECIFIC)
source	DEINOCOCCUS WULUMUQIENSIS
experiment	NMR
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
multimeric complexes	7lvv_AC 7lvv_BD
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7lvv_B interface=303,439,441,442,476,477,479,538,539,545,553,555,557,558,651,656,703,704,744,745,747,785,786,790, slqlvkkfqkrledivayggtrnessvraafqqllsdwaegsglrlitevtqkavagnnvrpdgtlkdslqqsrgyweskdeadtlddeiqkklakgyprdniifedsrlavlmqngeevqrvdmgdagalagllklffefeppqvlefrkavdhfkdemphllkilreaadaaeqkadyrgerdhfveiakeainpdfsprdaremliqhiltgdlftsvfdnaqyhednniaqqlqqlaatfykgpvkrdiaertkryygaiqaaaaqiadhhekqrflkalyenfyraynpagaerlgiFytpgeivrfmieatdtllekhfqkeladkgveildpatgtgtfitelidflpkakleqkyreelhcnelallpyyianlnieatyaqkmgryeefrnivlvdtldntgglfgsvtaenlerakrqnarpvrviigNpPYranqanendnnknreykeidrrikatyvaastaQKtKlydmysrflrwatdrlkedgivafvsnssfidsrtfdgfrkevvkdfdhiyildmkgnANtsgerRkreggnvFnDqIKvgvavyflvrsdtkiwyhavpdfwrareklewlkttkfediefdhirpdakhnwlgqvdeendwneflpvadkdtkqakglgqeraifklysLgvvtNrdewvysraedeladkvryfigryneiiklplgdlmsrnwegdikmTRatiadaqsrksysleknsivpslyrpfdvlkmyfsknlnEMqYqmpsifpkgvgenvvialsgspaakpfqvlatdilpsLDlleKtqclpfyrytmngerlnnitdyalkafqthyadtsisredifhyvyavlhhpayrekyalnlrqefpripfypefgrwaawgrelmalhigfesvapyplkrtdeppkndtpealalakkarlkvqrdaakqptgaveldglttlagipaaawayklgnrsalewvlerhkettpkdatirekfntyrfadhkervidllarvttvsvetvrivgempaetm
interface signature	FNPYQKKANRFDIKLNTREMYLDK

Estimated binding specificities ?

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# IC=10.224 IC/col=1.136 n_of_columns=9

specificity:

A |  19   0   0   0   0  96   0   0   0
C |  19   0   0  96  96   0   0   0  20
G |  39  96   0   0   0   0   0  96  76
T |  19   0  96   0   0   0  96   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----VANAYA----KTFAKAKGVA----HCTCRCEC   L                +---------------2ih2_D    
                                               +----------1 
  ----HANA----------AAACVAYCKG--------   L     !          +---------------5hr4_C    
                                             +-3 
  --QA--NAFA--------FA----------------       ! !   +----------------------2y7h_B    
                                           --4 +---2 
  YT----------MA----------------------       !     +----------------------6ymv_B    
                                             ! 
  ----------NT------------------------       +---------------------------6pa7_K

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updated Wed Dec 18 09:39:52 2024