7ml0_7AMOQRWX : 3D-footprint complex

structure name	RNA POLYMERASE II PRE-INITIATION COMPLEX (PIC1)
source	SACCHAROMYCES CEREVISIAE
experiment	NMR
structural superfamily	Cyclin-like;Zinc beta-ribbon;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;
reference complex	5oqj_M 5oqj_Q 5oqj_R 5oqj_X 7ml0_W
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7ml0_7 interface=334,443,501, padfvpdsvsgmfrshdfsylrlrpdhasrplwispsdgriilesfsplaeqaqdflvtiaepisrpshiheykitayslyaavsvgletddiisvldrlskvpvaesiinfikgatisygkvklvikhnryfvettqadilqmllndsvigplridsdhqvqppedvlereeedddidavhsfeianesvevvkkrcqeidypvleeydfrndhrnpdldidlkpstqirpyqekslskmfgngrarsgiivlpcgagktlvgitaactikksvivlctssvsvmqwrqqflqwctlqpencavftsdnkemfqtesglvvstysmvantrnRshdsqkvmdfltgrewgfiildevhvvpaamfrrvvstiaahaklgltatlvreddkigdlnfligpklyeanwmelsqkghianvqcaevwcpmtaefyqeylretaRkrmllyimnptkfqacqfliqyherrgdkiivfsdnvyalqeyalkmgkpfiygstpQqermnilqnfqyndqintiflskvgdtsidlpeatcliqisshygsrrqeaqrlgrilrakrrndegfnaffyslvskdtqemyystkrqaflvdqgyafkvithlhgmenipnlayasprerrellqevllkneea > 7ml0_A interface= gqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgsidrnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehnelmrqalaikdskkrfaaiwtlcktkmvcetdvpsrggcgntqptirkdglklvgswkkpelrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclpvppppvrpsisfnesqrgeddltfkladilkanisletlehngaphhaieeaesllqfhvatymdndiagqpqalqksgrpvksirarlkgkegrirgnlmgkrvdfsartviSgdpnleldqvgvpksiaktltypevvtpynidrltqlvrngpnehpgakyvirdsgdridlryskragdiqlqygwkverhimdndpvlfnrqpslhkmsmmahrvkvIpystfrlnlsvtspynadfdgdemnlhvpqseetraelsqlcavplqivspqsnkpcMgivqdtlcgirkltlrdtfieldqvlnmlywvpdwdgviptpaiikpkplwsgkqilsvaipngihlqrfdegttllspkdngmliidgqiifgvvekktvgssngglihvvtrekgpqvcaklfgniqkvvnfwllhngfstgigdtiadgptmreitetiaeakkkvldvtkeaqanlltakhgmtlresfednvvrflneardkagrlaevnlkdlnnvkqmvmagskgsfiniaqmsacvgqqsvegkriafgfvdrtlphfskddyspeskgfvensylrgltpqefffhamggreglidtavktaetgyiqrrlvkaledimvhydnttrnslgnviqfiygedgmdaahiekqsldtiggsdaafekryrvdllntdhtldpsllesgseilgdlklqvlldeeykqlvkdrkflrevfvdgeanwplpvnirriiqnaqqtfhidhtkpsdltikdivlgvkdlqenllvlrgkneiiqnaqrdavtlfccllrsrlatrrvlqeyrltkqafdwvlsnieaqflrsvvhpgemvgvlaaqsigepatqmkvtsgvprlkeilnvaknmktpsltvylepghaadqeqaklirsaiehttlksvtiaseiyydpdprstvipedeeiiqlhfsqqspwllrleldraamndkdltmgqvgerikqtfkndlfviwsedndekliircrvvaeedhmlkkientmlenitlrgveniervvmmkydrkvpsptgeyvkepewvletdgvnlsevmtvpgidptriytnsfidimevlgieagraalykevynviasdgsyvnyrhmallvdvmttqggltsvtrhgfnrsntgalmrcsfeetveilfeagasaelddcrgvsenvilgqmapigtgafdvmideeslvk > 7ml0_M interface= pnlnivltcpeckvyppkiverfsegdvvcalcglvlsdklvdtrsewrtfnplldgnnlstrigkgettdmrftkelnkaqgknvmdkkdnevqaafakitmlcdaaelpkivkdcakeayklchdektlkgksmesimaasiligcrraevartfkeiqslihvktkefgktlnimknilrgksqnltyiprfcshlglpmqvttsaeytakkckeikeiagkspitiavvsiylnillfqipitaakvgqtlqvtegtiksgykilyehrdklvdp > 7ml0_O interface=9,39,54,56,62,99,101,130,145,147,155, sgivptlqNivatvtlgcrldlktvalharnaeynpkrFaavimrirepkttaLiFasgkmVvtgakseddsklasrkyariiqkigfaakftdfkiqNiVgscdvkfpirleglafshgtfssyepelFpgliyrmvkpkivlLiFvsgkivlTgakqreeiyqafeaiypvlsefrkm > 7ml0_Q interface= fikrdrmrRnflrmreynefplraipkedlenmrthllKfqskkkinpvtdfhLpVrlhrkRktrqlkvldenakklrfeefypwvmedfyntwvgsyEaGnsdsyvllsveddgsftmipadkvykftArnkyatltideaekRmDk > 7ml0_R interface= dldlersnRqvwlvrlpmflaekwrlgkirinkskitlLlnepheydleltkkVvEneyvfTeqtipkktaivgtvchecqvmpyhkiveqrrnivklNnKerittldetvgvtmshtgmsmrsdnsnfLkvmpkkeildylfkLfDeydywslKglkertrqpeahlkecldkvatlvkkgpyafkytl > 7ml0_W interface= piddivknLlkfvvrgfyggsfvlvldailfhsvlaedDlkqllsinktelgpLiArlrsdRlisihkqreyppnsksvervyyyvkyphaidaikwkVhQvvqrlkddldknsepngymcpicltkytQleavqllnfdrtefLcSlcdeplvEddsgkknkekqdklnrlmdqiqpiidslkkiddsri > 7ml0_X interface= hdsskllwAteyiqkkgkpvlvnelldylsmkkddkviEllkkldriefdpkkGtFkylhsPsellkllrsqvtfkgisckdlkdgwpqcdetinqleEdSkilvlrtkkdktpryvwynsggnlkcidEefvkmwenvqlpqfAeLprklqdlGl
interface signature	RRQ/SIM//NFLFVNVFLFT/RKLVREGARD/RLVETNKLLDK/LDLARVQQLSE/AEGFPESEALG

Estimated binding specificities ?

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# IC=7.088 IC/col=0.148 n_of_columns=48

specificity:

A |   5  24  24  24  24  24  24  24   0  48  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0   6   5  96  24  24   0
C |   5  24  24  24  24  24  24  24  96  16  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0  16  17   0  24  24   0
G |   1  24  24  24  24  24  24  24   0  16  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0  10  16   0  24  24   0
T |  85  24  24  24  24  24  24  24   0  16  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  96  64  58   0  24  24  96

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updated Sun Dec 15 09:09:50 2024