structure nameRNA POLYMERASE II PRE-INITIATION COMPLEX (PIC3)
sourceSACCHAROMYCES CEREVISIAE
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;P-loop containing nucleoside triphosphate hydrolases;
reference complex5oqj_M 5oqj_O 5oqj_R 5oqj_U 5sva_Z 7ml0_W
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDRR/K/NVFLTNVFLVT/RVLVQNKLLSK/DVA

Estimated binding specificities ?

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# IC=9.643 IC/col=0.276 n_of_columns=35 specificity:   
A |  87   3  87   0  24  54  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   3   0  65   0  96
C |   3   5   3   0  24  17  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   3   0  13  96   0
G |   3   3   3   0  24  13  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  85   0  13   0   0
T |   3  85   3  96  24  12  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   5  96   5   0   0
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updated Fri Jun 26 14:18:24 2026