structure nameRNA POLYMERASE II PRE-INITIATION COMPLEX (PIC3)
sourceSACCHAROMYCES CEREVISIAE
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;P-loop containing nucleoside triphosphate hydrolases;
reference complex5oqj_M 5oqj_O 5oqj_R 5oqj_U 5sva_Z 7ml0_W
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDRR/K/NVFLTNVFLVT/RVLVQNKLLSK/DVA

Estimated binding specificities ?

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# IC=9.669 IC/col=0.276 n_of_columns=35 specificity:   
A |   0   0  12  96   3  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  16  24  96   3  85   5
C |   0   0  14   0  87  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  14  24   0   3   3   3
G |   0  96   3   0   3  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  10  24   0   5   5   3
T |  96   0  67   0   3  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  56  24   0  85   3  85
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updated Thu Jul 31 15:18:56 2025