structure nameRNA POLYMERASE II PRE-INITIATION COMPLEX (PIC3)
sourceSACCHAROMYCES CEREVISIAE
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;P-loop containing nucleoside triphosphate hydrolases;
reference complex5oqj_M 5oqj_O 5oqj_R 5oqj_U 5sva_Z 7ml0_W
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDRR/K/NVFLTNVFLVT/RVLVQNKLLSK/DVA

Estimated binding specificities ?

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# IC=10.180 IC/col=0.291 n_of_columns=35 specificity:   
A |   0   0  15  96   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  20  24  96   0  90   0
C |   0   0   5   0  96  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  21  24   0   0   5   5
G |   0  96  20   0   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  15  24   0   6   1   5
T |  96   0  56   0   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  40  24   0  90   0  86
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updated Wed Jan 7 04:16:34 2026