7nvu_ABEMORU : 3D-footprint complex

structure name	RNA POLYMERASE II CORE PRE-INITIATION COMPLEX WITH OPEN PROMOTER DNA
source	HOMO SAPIENS / SUS SCROFA
experiment	NMR
structural superfamily	Cyclin-like;Zinc beta-ribbon;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;
reference complex	5iy6_M 5iy6_N 5iy6_P 5iy6_T
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7nvu_A interface=1352, sacplrtikrvqfgvlspdelkrmsvteggikypetteggrpklgglmdprqgviertgrcqtcagnmtecpghfghielakpvfhvgflvktmkvlrcvcffcskllvdsnnpkikdilakskgqpkkrlthvydlckgkniceggcgryqprirrsglelyaewkkillspervheifkrisdeecfvlgmepryarpewmivtvlpvpplsvrpavvmqgsarnqddlthkladivkinnqlrrneqngaaahviaedvkllqfhvatmvdnelpglpramqksgrplkslkqrlkgkegrvrgnlmgkrvdfsartvitpdpnlsidqvgvprsiaanmtfaeivtpfnidrlqelvrrgnsqypgakyiirdngdridlrfhpkpsdlhlqtgykverhmcdgdivifnrqptlhkmsmmghrvrilpwstfrlnlsvttpynadfdgdemnlhlpqsletraeiqelamvprmivtpqsnrpvmgivqdtltavrkftkrdvflergevmnllmflstwdgkvpqpailkprplwtgkqifsliipghincirthsthpddedsgpykhispgdtkvvvengelimgilckkslgtsagslvhisylemghditrlfysniqtvinnwllieghtigigdsiadsktyqdiqntikkakqdvieviekahnneleptpgntlrqtfenqvnrilndardktgssaqkslseynnfksmvvsgakgskinisqviavvgqqnvegkripfgfkhrtlphfikddygpesrgfvensylagltptefffhamggreglidtavktaetgyiqrrliksmesvmvkydatvrnsinqvvqlrygedglagesvefqnlatlkpsnkafekkfrfdytneralrrtlqedlvkdvlsnahiqnelerefermredrevlrvifptgdskvvlpcnllrmiwnaqkifhinprlpsdlhpikvvegvkelskklvivngddplsrqaqenatllfnihlrstlcsrrmaeefrlsgeafdwllgeieskfnqaiahpgemvgalaaqslgepatqmtlnknvtlgvprlkeliniskkpktpsltvfllgqsardaerakdilcrlehttlrkvtantaiyydpnpqstvvaedqewvnvyyempdfdvarispwllrveldrkhmtdrkltmeqiaekinagfgddlncifnddnaeklvlririmnsdenkmdddvflrciesnmltdmtlqgieqiskvymhlpqtdnkkkiiitedgefkalqewiletdgvslmrvlsekdvdpvrttsndiveiftvlgieavrkalerelyhvisfdgsyvnyrhlallcdtmtcrghlmaitRhgvnrqdtgplmkcsfeetvdvlmeaaahgesdpmkgvsenimlgqlapagtgcfdllldaekckygmeip > 7nvu_B interface= deitpdlwqeacwivissyfdekglvrqqldsfdefiqmsvqrivedappidlqappryllkfeqiylskpthwerdgapspmmpnearlrnltysaplyvditktvikegeeqlqtqhqktfigkipimlrstycllngltdrdlcelnecpldpggyfiingsekvliaqekmatntvyvfakkdskyaytgecrsclenssrptstiwvsmlarggqgakksaigqrivatlpyikqevpiiivfralgfvsdrdilehiiydfedpemmemvkpsldeafviqeqnvalnfigsrgakpgvtkekrikyakevlqkemlphvgvsdfcetkkayflgymvhrlllaalgrrelddrdhygnkrldlagpllaflfrgmfknllkevriyaqkfidrgkdfnlelaiktriisdglkyslatgnwgdqkkahqaragvsqvlnrltfastlshlrrlnspigrdgklakprqlhntlwgmvcpaetpeghavglvknlalmayisvgsqpspilefleewsmenleeispaaiadatkifvngcwvgihkdpeqlmntlrklrrqmdiivsevsmirdirereiriytdagricrpllivekqklllkkrhidqlkereynnyswqdlvasgvveyidtleeetvmlamtpddlqekevaycstythceihpsmilgvcasiipfpdhnqsprntyqsamgkqamgvyitnfhvrmdtlahvlyypqkplvttrsmeylrfrelpaginsivaiasytgynqedsvimnrsavdrgffrsvfyrsykeqeskkgfdqeevfekptretcqgmrhaiydkldddgliapgvrvsgddviigktvtlptkrdcstflrtsetgivdqvmvtlnqegykfckirvrsvripqigdkfasrhgqkgtcgiqyrqedmpftcegitpdiiinphaipsrmtighlieclqgkvsankgeigdatpfndavnvqkisnllsdygyhlrgnevlyngftgrkitsqifigptyyqrlkhmvddkihsrargpiqilnrqpmegrsrdgglrfgemerdcqiahgaaqflrerlfeasdpyqvhvcnlcgimaiantrthtyecrgcrnktqislvrmpyackllfqelmsmsiaprmmsv > 7nvu_E interface= ddeeetyrlwkirktimqlchdrgylvtqdeldqtleefkaqfgdkpsegrprrtdltvlvahnddptdqmfvffpeepkvgiktikvycqrmqeenitralivvqqgmtpsakqslvdmapkyileqflqqellinitehelvpehvvmtkeevtellaryklrenqlpriqagdpvaryfgikrgqvvkiirpsetagryityrlvq > 7nvu_M interface=87,265,266, tcpnhpdailvedyragdmicpecglvvgdrvidvgsewrtftkdpsrvgdsqnpllsdgdlstmigkgtgaasfdefgnskyqnrRtmsssdrammnafkeittmadrinlprnivdrtnnlfkqvyeqkslkgrandaiasaclyiacrqegvprtfkeicavsriskkeigrcfklilkaletsvdlittgdfmsrfcsnlclpkqvqmaathiarkaveldlvpgrspisvaaaaiymasqasaekrtqkeigdiagvadVTirqsyrliyprapdlfptdfkfdtpvdklpql > 7nvu_O interface=9,11,39,54,56,62,64,99,101,130,131,145,147,153,155, sgivpqlqNiVstvnlgckldlktialrarnaeynpkrFaavimrireprttaLiFssgkmVcTgakseeqsrlaarkyarvvqklgfpakfldfkiqNmVgscdvkfpirleglvlthqqfssyepelFPgliyrmikprivlLiFvsgkvVlTgakvraeiyeafeniypilkgfrk > 7nvu_R interface=158, aergeldltgakqntgvwlvkvpkylsqqwakasgrgevgklriaktqgrtevsftlnedlanehpfvlqsvggqtltvftesssdklslegivvqraecrpaasenymrlkrlqieesskpvrlsqqldkvvttnykpvanhqynieyerkkkedgKraradkqhvldmlfsafekhqyynlkdlvditkqpvvylkeilkeigvqnvkgihkntwelkpe > 7nvu_U interface= tvpklyrsviedvindvrdiflddgvdeqvlmelktlwenklmgqveeeplnseddvsdeegqelfdtenvvvcqydkihrsknkwkfhlkdgimnlngrdyifskaigdaew
interface signature	R///RVT/NVFLFVTNVFPLFVT/K/

Estimated binding specificities ?

contact

# IC=11.674 IC/col=0.556 n_of_columns=21

specificity:

A |  14  24  24   0  96   7  96  96  96  96   0  14  24  24  24  24  24  24  24  24   0
C |   7  24  24   0   0   7   0   0   0   0   0   7  24  24  24  24  24  24  24  24   7
G |  66  24  24   0   0   7   0   0   0   0  96  68  24  24  24  24  24  24  24  24  82
T |   9  24  24  96   0  75   0   0   0   0   0   7  24  24  24  24  24  24  24  24   7

scan!

home
updated Wed Sep 11 09:37:45 2024