structure nameRNA POLYMERASE II PRE-INITIATION COMPLEX WITH CLOSED PROMOTER DNA IN DISTAL POSITION
sourceHOMO SAPIENS / SUS SCROFA
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;Eukaryotic RPB5 N-terminal domain;RPB5-like RNA polymerase subunit;
reference complex5iy6_M 5iy6_N 5iy6_P 5iy6_T 7nvy_E
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSHKKH/R/S/NVFALFVTNVFPLFVT/K/

Estimated binding specificities ?

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# IC=9.872 IC/col=0.210 n_of_columns=47 specificity:   
A |   0  96   7  96  96  56  96   6  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  11   0
C |   0   0   5   0   0  11   0   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  62  11
G |   6   0   5   0   0  11   0  90  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  16  85
T |  90   0  79   0   0  18   0   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   7   0
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updated Fri Jun 26 15:27:22 2026