interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE DIMERIC BRN2 (POU3F2) POU DOMAIN BOUND TO PALINDROMIC MORE DNA
(POU DOMAIN PROTEIN)
referenceTan et al. 'To ? ? ?
sourceMUS
experimentX-ray (resolution=1.89, R-factor=0.201)
structural superfamilylambda repressor-like DNA-binding domains;Homeodomain-like;
sequence familyPou domain Nterminal to homeobox domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSQTCRLNRVCNQ

Estimated binding specificities ?

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# IC=6.701 IC/col=0.957 n_of_columns=7 specificity:   
A |   8  96   0   0  19  69   0
C |  72   0   0   0  61  11   0
G |   8   0   0  96   8   8   0
T |   8   0  96   0   8   8  96
scan!

Dendrogram of similar interfaces ?

matrix format
  
  SGQATG--CARG--------   L     +-----------------------------8g87_X    
                             +-2 
  SGQATT----RG--------   L   ! !            +----------------1o4x_A    
                           --3 +------------1 
  ------------ITQCNAMC   L   !              +----------------2r5y_A    
                             ! 
  TTQA--LTSAET--------   L   +-----------------------------2o4a_A    
                           

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updated Wed Dec 18 14:11:39 2024