interface graph thumbnail
legend  pdf

structure nameCRYO-EM STRUCTURE OF HUMAN TOPOISOMERASE II BETA IN COMPLEX WITH DNA AND ETOPOSIDE
experimentNMR
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A;
redundant complexes5zen_A 5zqf_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKQIR

Estimated binding specificities ?

contactlogo
# IC=3.142 IC/col=0.628 n_of_columns=5 specificity:   
A |   0  96  24  13  16
C |  96   0  24  13  13
G |   0   0  24  57  13
T |   0   0  24  13  54
scan!

home
updated Tue Jun 30 12:09:13 2026