interface graph thumbnail
legend  pdf

structure nameCRYO-EM STRUCTURE OF HUMAN TOPOISOMERASE II BETA IN COMPLEX WITH DNA AND ETOPOSIDE
experimentNMR
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A;
redundant complexes5zen_A 5zqf_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKQIR

Estimated binding specificities ?

contactlogo
# IC=3.101 IC/col=0.620 n_of_columns=5 specificity:   
A |  54  13  24   0   0
C |  16  54  24   0   0
G |  13  16  24   0  96
T |  13  13  24  96   0
scan!

home
updated Sat Jan 10 20:49:43 2026