interface graph thumbnail
legend  pdf

structure nameOCT4/SOX2 PROTEIN:DNA COMPLEX
referenceChojnowski et al. 'To ? ? ?
experimentX-ray (resolution=2.50, R-factor=?)
structural superfamilyHMG-box;lambda repressor-like DNA-binding domains;Homeodomain-like;
reference complex1o4x_B 8bx1_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQSQTTSRVSNQ/RNFMRNSSY

Estimated binding specificities ?

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# IC=16.463 IC/col=1.029 n_of_columns=16 specificity:   
A |   5  10   0   5  24   0   6  90   0   5  96   0  96  96  96   5
C |  80   0   0  12  24   0  85   0   0   5   0  96   0   0   0   5
G |   5   0   0  10  24  96   0   6   0  81   0   0   0   0   0  81
T |   6  86  96  69  24   0   5   0  96   5   0   0   0   0   0   5
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updated Fri Aug 1 05:25:59 2025