interface graph thumbnail
legend  pdf

structure nameOCT4/SOX2 PROTEIN:DNA COMPLEX
referenceChojnowski et al. 'To ? ? ?
experimentX-ray (resolution=2.50, R-factor=0.254)
structural superfamilylambda repressor-like DNA-binding domains;Homeodomain-like;
sequence familyPou domain Nterminal to homeobox domain;
multimeric complexes3l1p_AB 6ht5_DE 8bx1_AE 8bx2_AE
redundant complexes3l1p_A 8bx2_A 6ht5
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQSQTTSRVSNQ

Estimated binding specificities ?

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# IC=8.534 IC/col=0.853 n_of_columns=10 specificity:   
A |   9  96   1   6   0  24  61  96  82   6
C |  75   0   6   2  96  24  13   0   0   6
G |   6   0   0  82   0  24   6   0   1  82
T |   6   0  89   6   0  24  16   0  13   2
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updated Sat Sep 14 09:15:44 2024