8bx1_A : 3D-footprint complex

structure name	OCT4/SOX2 PROTEIN:DNA COMPLEX
reference	Chojnowski et al. 'To ? ? ?
experiment	X-ray (resolution=2.50, R-factor=0.254)
structural superfamily	lambda repressor-like DNA-binding domains;Homeodomain-like;
sequence family	Pou domain Nterminal to homeobox domain;
multimeric complexes	3l1p_AB 6ht5_DE 8bx1_AE 8bx2_AE
redundant complexes	3l1p_A 8bx2_A 6ht5
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8bx1_A interface=30,46,47,48,49,51,52,117,120,121,124, gamdmkalqkeleqfakllkqkritlgytQadvgltlgvlfgkvfSQTTiSRfealqlslknmsklrpllekwveeadnnrvrwsletmflkspkpslqqithianqlglekdvvrVwfSNrrQkgk
interface signature	QSQTTSRVSNQ

Estimated binding specificities ?

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# IC=8.859 IC/col=0.886 n_of_columns=10

specificity:

A |   6  96   0   6   0  24  61  96  83  13
C |  75   0   0   0  96  24  13   0   0   0
G |   9   0   0  84   0  24   9   0   0  77
T |   6   0  96   6   0  24  13   0  13   6

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updated Wed Dec 18 16:21:58 2024