interface graph thumbnail
legend  pdf

structure nameOCT4/SOX2 PROTEIN:DNA COMPLEX
referenceChojnowski et al. 'To ? ? ?
experimentX-ray (resolution=3.14, R-factor=?)
structural superfamilyHMG-box;lambda repressor-like DNA-binding domains;Homeodomain-like;
reference complex1o4x_B 8bx1_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQTSR/RNFMRNSYR

Estimated binding specificities ?

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# IC=14.377 IC/col=0.958 n_of_columns=15 specificity:   
A |   6  89   0   0   0   0   8  96   0   6   0  13  24  24   7
C |  78   0   0   0   0   0   6   0   0   6  96   8  24  24   0
G |   6   6   0   0  96   0   0   0   0  78   0   0  24  24   0
T |   6   1  96  96   0  96  82   0  96   6   0  75  24  24  89
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updated Fri Aug 1 05:26:16 2025