interface graph thumbnail
legend  pdf

structure nameOCT4/SOX2 PROTEIN:DNA COMPLEX
referenceChojnowski et al. 'To ? ? ?
experimentX-ray (resolution=3.14, R-factor=?)
structural superfamilyHMG-box;lambda repressor-like DNA-binding domains;Homeodomain-like;
reference complex1o4x_B 8bx1_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQTSR/RNFMRNSYR

Estimated binding specificities ?

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# IC=14.240 IC/col=0.949 n_of_columns=15 specificity:   
A |   7  88   0   0   0   0   7  96   0   7   0  14  24  24   7
C |  81   0   0   0   0   0   0   0   0   9  96   9  24  24   1
G |   7   8   0   0  96   0   1   0   0  73   0   7  24  24   0
T |   1   0  96  96   0  96  88   0  96   7   0  66  24  24  88
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updated Wed Jan 7 20:05:05 2026