interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAAGCGGAAGTGGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=1.28, R-factor=0.128)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQKRARN

Estimated binding specificities ?

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# IC=3.496 IC/col=0.250 n_of_columns=14 specificity:   
A |  24  24  24  24  21  21   6   4   0   6  24  24  24  24
C |  24  24  24  24  31  23   6  81  96   6  24  24  24  24
G |  24  24  24  24  21  21   6   7   0  78  24  24  24  24
T |  24  24  24  24  23  31  78   4   0   6  24  24  24  24
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updated Tue Dec 19 02:53:02 2023