interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN BOUND TO D(AATAAGCGGAAGTGGG) ACETATE FREE AT PH 5.4
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=1.32, R-factor=0.149)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQKRARN

Estimated binding specificities ?

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# IC=3.387 IC/col=0.242 n_of_columns=14 specificity:   
A |  24  24  24  24  22  21   6   4   0   7  24  24  24  24
C |  24  24  24  24  27  21   6  81  96   7  24  24  24  24
G |  24  24  24  24  25  23   6   7   0  74  24  24  24  24
T |  24  24  24  24  22  31  78   4   0   8  24  24  24  24
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updated Tue Dec 19 02:54:47 2023