interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAAGCGGAATGGGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=1.33, R-factor=0.140)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes8ek8_EF
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQKRARN

Estimated binding specificities ?

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# IC=4.126 IC/col=0.825 n_of_columns=5 specificity:   
A |  10  12   0   0  10
C |  10  10  96  96  10
G |  12  10   0   0  76
T |  64  64   0   0   0
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updated Sat Aug 2 23:47:39 2025