8ek3_F : 3D-footprint complex

structure name	HUMAN PU.1 ETS-DOMAIN (165-270) Q226E MUTANT BOUND TO D(AATAAGCGGAATGGGG) (Transcription factor PU.1)
reference	Terrell et al. 'Cell 42 112671 2023
source	Homo sapiens
experiment	X-ray (resolution=1.38, R-factor=0.143)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Etsdomain;
reference complex	8ee9_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8ek3_F interface=58,59,62,63,65,66, kirlyqflldllrsgdmkdsiwwvdkdkgtfqfsskhkealahrwgiqkgnrkkmtyEKmaRAlRNygktgevkkvkkkltyqfsgevlgr
interface signature	EKRARN

Estimated binding specificities ?

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# IC=3.382 IC/col=0.242 n_of_columns=14

specificity:

A |  24  24  24  24  24  21   4   4   0   8  24  24  24  24
C |  24  24  24  24  24  21   4  81  96   8  24  24  24  24
G |  24  24  24  24  24  23   7   7   0  70  24  24  24  24
T |  24  24  24  24  24  31  81   4   0  10  24  24  24  24

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updated Tue Dec 19 03:08:35 2023