interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAAAAGGAGAAGGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=2.63, R-factor=0.241)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes8ek8_EF
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQKRARN

Estimated binding specificities ?

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# IC=4.154 IC/col=0.831 n_of_columns=5 specificity:   
A |  21   0  85   0  66
C |  23   0   0   0  10
G |  42  96  10  96  10
T |  10   0   1   0  10
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updated Fri Sep 13 10:45:02 2024