8ek8_E : 3D-footprint complex

structure name	HUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAAAAGGAGAAGGG) (Transcription factor PU.1)
reference	Terrell et al. 'Cell 42 112671 2023
source	Homo sapiens
experiment	X-ray (resolution=2.63, R-factor=0.241)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Etsdomain;
reference complex	8ee9_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8ek8_E interface=58,59,62,63,65,66, kirlyqflldllrsgdmkdsiwwvdkdkgtfqfsskhkealahrwgiqkgnrkkmtyQKmaRAlRNygktgevkkvkkkltyqfsgevlg
interface signature	QKRARN

Estimated binding specificities ?

readout + contact

# IC=4.261 IC/col=0.142 n_of_columns=30

specificity:

A |  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  23   6   6   0   0  14  24  24  24  24  24  24
C |  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  21   6  78   0  96  54  24  24  24  24  24  24
G |  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  21   6   6   0   0  14  24  24  24  24  24  24
T |  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  31  78   6  96   0  14  24  24  24  24  24  24

scan!

home
updated Tue Dec 19 03:08:39 2023